RTN4R and ZDHHC8

Data Source:
BioGRID (affinity chromatography technology)

		RTN4R	ZDHHC8
Description		reticulon 4 receptor	zinc finger DHHC-type palmitoyltransferase 8
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Anchored Component Of External Side Of Plasma Membrane Neuron Projection Neuronal Cell Body Dendritic Shaft Perikaryon Axonal Growth Cone Membrane Raft Extracellular Exosome	Golgi Membrane Golgi Apparatus Cytosol Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Heparin Binding Chondroitin Sulfate Binding Signaling Receptor Activity Neuregulin Receptor Activity Ganglioside GM1 Binding Ganglioside GT1b Binding	Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Cell Surface Receptor Signaling Pathway Negative Regulation Of Neuron Projection Development Corpus Callosum Development Neuronal Signal Transduction Negative Regulation Of Axon Extension Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Negative Regulation Of Axon Regeneration Negative Regulation Of Axonogenesis	Locomotory Behavior Positive Regulation Of Cholesterol Efflux Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation High-density Lipoprotein Particle Assembly Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Axonal growth inhibition (RHOA activation)	HDL assembly
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Obesity-related traits ( 23251661)
Interacting Genes		9 interacting genes: HOXA1 LINGO1 MAG MGAT5B NGFR OMG OTX1 RTN4 RTN4IP1
Entrez ID		65078	29801
HPRD ID		16123	12298
Ensembl ID		ENSG00000040608	ENSG00000099904
Uniprot IDs		Q9BZR6	Q9ULC8
PDB IDs		1OZN 1P8T
Enriched GO Terms of Interacting Partners?
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