SKIV2L and WDR1

Data Source:
HPRD (two hybrid)

		SKIV2L	WDR1
Description		Ski2 like RNA helicase	WD repeat domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Ski Complex	Podosome Extracellular Region Cytosol Plasma Membrane Cell-cell Junction Cell Junction Cortical Actin Cytoskeleton Cell Projection Extracellular Exosome
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding	Actin Filament Binding
	Biological Process	RNA Catabolic Process Exonucleolytic Catabolism Of Deadenylated MRNA Nuclear-transcribed MRNA Catabolic Process, 3'-5' Exonucleolytic Nonsense-mediated Decay	Neutrophil Mediated Immunity Platelet Degranulation Sensory Perception Of Sound Regulation Of Cell Shape Actin Filament Depolymerization Actin Filament Fragmentation Platelet Formation Regulation Of Actin Filament Depolymerization Positive Regulation Of Actin Filament Depolymerization Cortical Cytoskeleton Organization Locomotion Establishment Of Planar Polarity Of Follicular Epithelium Apical Junction Assembly Maintenance Of Epithelial Cell Apical/basal Polarity Sarcomere Organization Regulation Of Oligodendrocyte Differentiation Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Neutrophil Migration
Pathways		Association of TriC/CCT with target proteins during biosynthesis mRNA decay by 3' to 5' exoribonuclease	Platelet degranulation
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 23577725 20861866) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood metabolite levels ( 24816252) Blood protein levels ( 29875488 28240269) Coronary artery disease ( 29212778) Disease progression in age-related macular degeneration ( 29346644) Inflammatory bowel disease ( 28067908) Platelet count ( 32888494) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908) vWF levels ( 30586737)	Atrial fibrillation ( 29892015) Cardiovascular disease risk factors ( 21943158) Cleft plate (environmental tobacco smoke interaction) ( 24516586) Estimated glomerular filtration rate ( 31152163) Pulse pressure ( 30224653) Schizophrenia (age at onset) ( 21688384) Serum uric acid levels ( 32514006) Urate levels ( 18179892 31578528) Uric acid levels ( 22229870)
Interacting Genes		14 interacting genes: CACNB3 CDK11A CDKL5 EXOSC10 EXOSC4 GALNT13 PMPCA PRKAA2 RHOU SNRPB TNRC17 TSSK2 WDR1 XRN1	6 interacting genes: CARD11 CFL1 CSNK2B GRB2 HSPB2 SKIV2L
Entrez ID		6499	9948
HPRD ID		02724	09199
Ensembl ID		ENSG00000204351	ENSG00000071127
Uniprot IDs		A0A1U9X8J1 Q15477	O75083 V9HWG7
PDB IDs
Enriched GO Terms of Interacting Partners?
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