PLA2G2F and VENTX

Data Source:
BioGRID (two hybrid)

		PLA2G2F	VENTX
Description		phospholipase A2 group IIF	VENT homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane	Chromatin Nucleus
	Molecular Function	Phospholipase A2 Activity Calcium Ion Binding Phospholipid Binding Calcium-dependent Phospholipase A2 Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Lipid Catabolic Process Arachidonic Acid Metabolic Process Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylinositol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Negative Regulation Of T Cell Proliferation Innate Immune Response Arachidonic Acid Secretion	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA	Senescence-Associated Secretory Phenotype (SASP) Transcriptional Regulation by VENTX
Drugs
Diseases
GWAS		group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)
Interacting Genes		3 interacting genes: MICOS10-NBL1 NBL1 VENTX	93 interacting genes: ABHD11 ADAMTSL4 ARID5A ARSA ATXN7L1 BATF2 BHLHE40 C10orf55 C19orf54 C1orf94 C6orf15 CEACAM6 CERCAM CES1 CFP CREM CSN3 CTAG1A CTAG1B CYSRT1 DAB1 DAZAP2 FAM168B FAM86C1P GLIS2 HOXC8 HYPK INTS11 IRF9 ITIH6 KRT34 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-4 KRTAP13-1 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LITAF LYG1 MAGED1 MIEN1 ODAM PLA2G2F PLEKHB1 POU6F2 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX1 RBPMS RHOXF2 RNF144B RNF4 ROR2 RSKR SLC15A2 SMUG1 SOX14 SPRY4 SYNGAP1 TBX15 TBX19 TBX22 TEKT5 TLE2 TMBIM4 TMEM42 TRIP13 TSC1 UBAP2 UBE2I UBQLN2 USP54 VAC14 VHLL WWOX YPEL3 ZBTB32 ZNF34
Entrez ID		64600	27287
HPRD ID		07499	06197
Ensembl ID		ENSG00000158786	ENSG00000151650
Uniprot IDs		Q9BZM2	O95231
PDB IDs
Enriched GO Terms of Interacting Partners?
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