TEKT3 and AJUBA

Data Source:
BioGRID (two hybrid)

		TEKT3	AJUBA
Description		tektin 3	ajuba LIM protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Outer Acrosomal Membrane Nucleus Microtubule Cytoskeleton Sperm Flagellum Extracellular Exosome	P-body Nucleus Nucleoplasm Transcription Regulator Complex Golgi Apparatus Microtubule Organizing Center Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Focal Adhesion Lamellipodium
	Molecular Function	Molecular_function Protein Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Alpha-catenin Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility Regulation Of Brood Size	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Response To Hypoxia Regulation Of Transcription, DNA-templated Cytoskeleton Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lamellipodium Assembly Regulation Of Cell Migration Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Protein-containing Complex Assembly Negative Regulation Of Kinase Activity Cellular Protein Localization Gene Silencing By MiRNA Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Hippo Signaling Regulation Of GTPase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Glycerophospholipid Biosynthetic Process Focal Adhesion Assembly Regulation Of Cellular Response To Hypoxia Positive Regulation Of Gene Silencing By MiRNA
Pathways			Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Regulation of PLK1 Activity at G2/M Transition Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Insular cortex volume ( 31530798) Macular thickness ( 30535121) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Spatial processing ( 31596458)
Interacting Genes		33 interacting genes: AJUBA ARID5A ASPG ATN1 CALCOCO2 CNOT2 DDI1 GORASP2 HNRNPH1 IKZF3 INSC KRT34 KRTAP15-1 KRTAP19-5 KRTAP26-1 KRTAP3-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 LMO2 METTL27 OIP5 PLAGL2 PLEKHG4 RAMAC RFX6 SPAG8 TEX45 TNS2 TRAF2 TRIB3 WWOX	20 interacting genes: ACTA1 AURKAIP1 AURKB BCAR1 CATSPER1 CREB5 CTNNA1 FARS2 GFI1B GRB2 LATS2 LCK LGALS14 PIN1 SLC1A2 TEKT3 TFAP4 TSG101 ZNF512B ZNF541
Entrez ID		64518	84962
HPRD ID		18173	16426
Ensembl ID		ENSG00000125409	ENSG00000129474
Uniprot IDs		Q9BXF9	Q96IF1
PDB IDs
Enriched GO Terms of Interacting Partners?
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