BLVRB and RPL31

Data Source:
BioGRID (two hybrid)

		BLVRB	RPL31
Description		biliverdin reductase B	ribosomal protein L31
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Extracellular Exosome
	Molecular Function	Biliverdin Reductase (NAD(P)+) Activity Protein Binding Riboflavin Reductase (NADPH) Activity Biliberdin Reductase NAD+ Activity Biliverdin Reductase (NADP+) Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Heme Catabolic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways		Heme degradation	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Riboflavin NADH Biliverdine IX Alpha Flavin mononucleotide Nicotinamide adenine dinucleotide phosphate Lumichrome Mesobiliverdin IV alpha
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		4 interacting genes: ANXA10 HMOX1 ORM1 RPL31	10 interacting genes: APP BLVRB BRCA1 CACNA1A CRKL DUX4 EWSR1 GPR20 IL7R PTEN
Entrez ID		645	6160
HPRD ID		02967	17994
Ensembl ID		ENSG00000090013	ENSG00000071082
Uniprot IDs		P30043 V9HWI1	P62899
PDB IDs		1HDO 1HE2 1HE3 1HE4 1HE5 5OOG 5OOH 6OPL	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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