TRA2B and MIR19B1

Data Source:
BioGRID (unspecified method)

		TRA2B	MIR19B1
Description		transformer 2 beta homolog	microRNA 19b-1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Nucleoplasm Spliceosomal Complex Protein-containing Complex Perinuclear Region Of Cytoplasm	Extracellular Space Perinuclear Region Of Cytoplasm Blood Microparticle Extracellular Vesicle
	Molecular Function	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Pre-mRNA Binding Identical Protein Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Response To Reactive Oxygen Species RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Cerebral Cortex Regionalization Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Glucose Stimulus Embryonic Brain Development	Negative Regulation Of Inflammatory Response To Antigenic Stimulus Positive Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Interleukin-6 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Cholesterol Homeostasis Negative Regulation Of Coagulation Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Bacterial Lipopeptide Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Cholesterol Efflux Regulation Of Plasma Lipoprotein Particle Levels Negative Regulation Of Serine-type Endopeptidase Activity Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Negative Regulation Of Reverse Cholesterol Transport Negative Regulation Of Matrix Metallopeptidase Secretion Positive Regulation Of Apoptotic Process Involved In Development Negative Regulation Of Apolipoprotein A-I-mediated Signaling Pathway
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Height ( 31562340) Menarche (age at onset) ( 27182965 21102462 25231870) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		110 interacting genes: CDK6 CLK1 CLK3 EPM2AIP1 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM MAGOHB MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYPOP NGFR NXF1 PCDHB14 RBMX RBMXL2 RBMY1A1 RBMY1F RBMY1J RNPS1 SREK1 SRPK1 SRPK2 SRSF1 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF8 SRSF9 TNPO3 U2AF1 U2AF1L5 YTHDC1 YWHAG YWHAZ ZRANB2	103 interacting genes: AIMP1 AIMP2 APOBEC3B AQR C1QBP CELF1 CELF2 CPSF1 CPSF2 CPSF3 CPSF4 CPSF6 CPSF7 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT21 P3H1 PATL1 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBBP6 RBFOX2 RBM12B RBM14 RBM4 RBMS2 RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 WDR33 WWP1 WWP2 YBX1 YBX2 YBX3 ZNF346 ZNF385A
Entrez ID		6434	406980
HPRD ID		04097
Ensembl ID		ENSG00000136527	ENSG00000284375
Uniprot IDs		P62995
PDB IDs		2CQC 2KXN 2RRA 2RRB
Enriched GO Terms of Interacting Partners?
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