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FAM25A and PPIF
Data Source:
BioGRID
(two hybrid)
FAM25A
PPIF
Description
family with sequence similarity 25 member A
peptidylprolyl isomerase F
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Mitochondrial Proton-transporting ATP Synthase Complex
Mitochondrial Permeability Transition Pore Complex
Mitochondrial Matrix
Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Peptidyl-prolyl Cis-trans Isomerase Activity
Protein Binding
Cyclosporin A Binding
Biological Process
Protein Peptidyl-prolyl Isomerization
Response To Ischemia
Protein Folding
Apoptotic Mitochondrial Changes
Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism
Regulation Of Necrotic Cell Death
Negative Regulation Of ATPase Activity
Negative Regulation Of Apoptotic Process
Regulation Of Mitochondrial Membrane Permeability
Necroptotic Process
Cellular Response To Hydrogen Peroxide
Cellular Response To Arsenic-containing Substance
Cellular Response To Calcium Ion
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Negative Regulation Of Oxidative Phosphorylation
Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death
Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death
Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Cyclosporine
Proline
Triglyme
Coumarin 120
Diseases
GWAS
Blood protein levels (
30072576
)
Height (
20881960
31562340
)
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Immature fraction of reticulocytes (
32888494
)
Mean platelet volume (
32888494
)
Metabolite levels (
23823483
)
Triglyceride levels (
32203549
)
Interacting Genes
18 interacting genes:
ARMC10
ARMCX3
COX16
GPD1
IGLL1
KLHL35
LCN1
LCN2
MIEF1
MIEF2
PPIC
PPIF
S100A6
SNX1
TDRKH
TOMM20L
TTPA
ZFAND3
19 interacting genes:
ABI2
AGTRAP
ARFIP2
BANP
CIDEB
CMTM5
FAM25A
FAM25C
FAM25G
FKBP7
MAGEA11
MUC1
PRB3
SERPINB5
SLC25A4
SYP
SYPL1
VDAC1
YIF1A
Entrez ID
643161
10105
HPRD ID
06839
Ensembl ID
ENSG00000188100
ENSG00000108179
Uniprot IDs
B3EWG3
B3EWG5
B3EWG6
A0A024QZS4
P30405
PDB IDs
2BIT
2BIU
2Z6W
3QYU
3R49
3R4G
3R54
3R56
3R57
3R59
3RCF
3RCG
3RCI
3RCK
3RCL
3RD9
3RDA
3RDB
3RDC
4J58
4J59
4J5A
4J5B
4J5C
4J5D
4J5E
4O8H
4O8I
4XNC
4ZSC
4ZSD
5A0E
5CBT
5CBU
5CBV
5CBW
5CCN
5CCQ
5CCR
5CCS
6R8L
6R8O
6R8W
6R9S
6R9U
6R9X
6RA1
6Y3E
6YBM
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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