SRSF1 and LUC7L3

Data Source:
HPRD (two hybrid, in vitro)

		SRSF1	LUC7L3
Description		serine and arginine rich splicing factor 1	LUC7 like 3 pre-mRNA splicing factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding DNA Topoisomerase Binding	DNA Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing	MRNA Splice Site Selection RNA Splicing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Copper
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Mild to moderate chronic kidney disease ( 31178898)
Interacting Genes		43 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK6 CLK1 DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PPARG PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF4 SRSF5 TCERG1 TNPO3 TOP1 TP53 TRA2B U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2	9 interacting genes: CLK1 ITSN2 MLH1 RNPS1 SRPK1 SRPK2 SRSF1 TLR10 YWHAG
Entrez ID		6426	51747
HPRD ID		02887	16759
Ensembl ID		ENSG00000136450	ENSG00000108848
Uniprot IDs		Q07955 Q59FA2	A8K3C5 J3KPP4 O95232 Q86Y74
PDB IDs		1X4A 2M7S 2M8D 2O3D 3BEG 4C0O
Enriched GO Terms of Interacting Partners?
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