CIDEC and NR0B2

Data Source:
BioGRID (two hybrid)

		CIDEC	NR0B2
Description		cell death inducing DFFA like effector c	nuclear receptor subfamily 0 group B member 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Lipid Droplet Cytosol	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex
	Molecular Function	Molecular_function Protein Binding	Transcription Corepressor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Protein Homodimerization Activity Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding Transcription Regulator Inhibitor Activity
	Biological Process	Apoptotic Process Lipid Droplet Organization Regulation Of Apoptotic Process Execution Phase Of Apoptosis	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Circadian Rhythm Cholesterol Metabolic Process Response To Glucose Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Bile Acid And Bile Salt Transport Animal Organ Regeneration Positive Regulation Of Insulin Secretion Circadian Regulation Of Gene Expression Negative Regulation Of DNA-binding Transcription Factor Activity Response To Ethanol Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		Lipid particle organization	Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) HDL cholesterol ( 24097068) LDL cholesterol ( 24097068) Triglycerides ( 24097068)
Interacting Genes		7 interacting genes: CIDEA KLHL20 METTL15 NR0B2 SPATA12 UFSP1 ZBTB42	51 interacting genes: AR CHRD CIDEC DDX20 EID1 ESR1 ESR2 ESRRA ESRRG FN1 GPS2 GPSM3 HDAC3 HDAC6 HNF4A HNF4G HNRNPA1 ID2 IL3RA NCOA3 NEUROD1 NR1H2 NR1H3 NR1I2 NR1I3 NR3C1 NR5A2 PAX9 PEF1 PLSCR1 POLR2A PPARD PPARG RARA RARG RBP5 RNF31 RXRA RXRB RXRG SMAD4 SMARCA2 SMARCB1 SMARCE1 SNW1 THRA TP53 VDR XBP1 ZAP70 ZMYND10
Entrez ID		63924	8431
HPRD ID		13060	05219
Ensembl ID		ENSG00000187288	ENSG00000131910
Uniprot IDs		A0A0A0MRY9 Q96AQ7	Q15466
PDB IDs			1YUC 2Q3Y 2Z4J 4DOR 4ONI 5UFS 6W9M
Enriched GO Terms of Interacting Partners?
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