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SCTR and ADCYAP1
Data Source:
BioGRID
(unspecified method, unspecified method)
HPRD
(in vivo, in vitro)
SCTR
ADCYAP1
Description
secretin receptor
adenylate cyclase activating polypeptide 1
Image
GO Annotations
Cellular Component
Cytoplasmic Microtubule
Plasma Membrane
Integral Component Of Membrane
Extracellular Region
Extracellular Space
Neuron Projection
Terminal Bouton
Perikaryon
Molecular Function
G Protein-coupled Peptide Receptor Activity
Secretin Receptor Activity
Peptide Hormone Binding
Signaling Receptor Binding
Neuropeptide Hormone Activity
Protein Binding
Pituitary Adenylate Cyclase Activating Polypeptide Activity
Pituitary Adenylate Cyclase-activating Polypeptide Receptor Binding
Peptide Hormone Receptor Binding
Biological Process
Diet Induced Thermogenesis
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Brain Development
Cellular Water Homeostasis
Response To Nutrient Levels
Regulation Of Appetite
Positive Regulation Of CAMP-mediated Signaling
Regulation Of Synaptic Plasticity
Ovarian Follicle Development
Behavioral Fear Response
Histamine Secretion
Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Negative Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Activation Of Adenylate Cyclase Activity
Positive Regulation Of Cytosolic Calcium Ion Concentration
Neuropeptide Signaling Pathway
Cell-cell Signaling
Female Pregnancy
Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Muscle Cell Apoptotic Process
Positive Regulation Of Neuron Projection Development
Sensory Perception Of Pain
CAMP-mediated Signaling
Pituitary Gland Development
Insulin Secretion
Neuron Projection Development
Positive Regulation Of Interleukin-6 Production
Regulation Of Protein Localization
Negative Regulation Of GTPase Activity
Response To Starvation
Negative Regulation Of Potassium Ion Transport
Positive Regulation Of GTPase Activity
Positive Regulation Of CAMP-mediated Signaling
Response To Ethanol
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
ATP Metabolic Process
Positive Regulation Of Synaptic Transmission, Glutamatergic
Regulation Of Postsynaptic Membrane Potential
Positive Regulation Of Growth Hormone Secretion
Negative Regulation Of Glial Cell Proliferation
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Oligodendrocyte Progenitor Proliferation
Cellular Response To Glucocorticoid Stimulus
Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production
Positive Regulation Of Somatostatin Secretion
Positive Regulation Of Cold-induced Thermogenesis
Pathways
G alpha (s) signalling events
Glucagon-type ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
NGF-independant TRKA activation
G alpha (s) signalling events
Glucagon-type ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Secretin human
2,6-Diamino-Hexanoic Acid Amide
Diseases
GWAS
Bipolar disorder (
31043756
)
Type 2 diabetes (
32499647
30718926
)
Body size at age 10 (
32376654
)
Chronotype (
30696823
)
Midgestational cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Obesity-related traits (
23251661
)
Very long-chain saturated fatty acid levels (fatty acid 22:0) (
25378659
)
Interacting Genes
9 interacting genes:
ADCYAP1
CALM1
CPAMD8
CYFIP1
DNAL4
PRKAR2A
PRKCA
SCT
SNTA1
8 interacting genes:
ADCYAP1R1
CASP2
CPAMD8
MME
SCTR
SHH
VIPR1
VIPR2
Entrez ID
6344
116
HPRD ID
01628
02369
Ensembl ID
ENSG00000080293
ENSG00000141433
Uniprot IDs
P47872
Q8IV17
B7Z222
P18509
PDB IDs
6WI9
6WZG
7D3S
1GEA
2D2P
2JOD
6LPB
6M1I
6P9Y
6VN7
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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