RRM2 and BARX1

Data Source:
BioGRID (two hybrid)

		RRM2	BARX1
Description		ribonucleotide reductase regulatory subunit M2	BARX homeobox 1
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GO Annotations	Cellular Component	Cytosol	Chromatin Nucleus
	Molecular Function	Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Protein Binding Metal Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle DNA Replication Deoxyribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Negative Regulation Of G0 To G1 Transition	Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Anterior/posterior Pattern Specification Negative Regulation Of Wnt Signaling Pathway Epithelial Cell Differentiation Spleen Development Digestive System Development
Pathways		Interconversion of nucleotide di- and triphosphates G1/S-Specific Transcription Transcriptional Regulation by E2F6
Drugs		Cladribine Imexon Gallium nitrate Motexafin gadolinium GTI 2040
Diseases
GWAS		Kidney function decline traits ( 25493955) Prostate cancer ( 23535732)	Barrett's esophagus ( 24121790) Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined) ( 24121790) Esophageal adenocarcinoma ( 24121790) Heel bone mineral density ( 28869591) Parkinson's disease ( 26227905) Serum folate levels ( 29953918)
Interacting Genes		9 interacting genes: CDH1 CDK1 DNM1L KAT5 PLK3 RRM1 RRM2B SDCBP TP53	5 interacting genes: CYP17A1 HOXD9 MAPK6 RPS6KA3 UBC
Entrez ID		6241	56033
HPRD ID		01587	16017
Ensembl ID		ENSG00000171848	ENSG00000131668
Uniprot IDs		P31350	Q9HBU1
PDB IDs		2UW2 3OLJ 3VPM 3VPN 3VPO	2DMT
Enriched GO Terms of Interacting Partners?
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