RRM2 and MGAT4A

Data Source:
BioGRID (two hybrid)

		RRM2	MGAT4A
Description		ribonucleotide reductase regulatory subunit M2	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Stack Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Protein Binding Metal Ion Binding	Acetylglucosaminyltransferase Activity Alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle DNA Replication Deoxyribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Negative Regulation Of G0 To G1 Transition	Protein N-linked Glycosylation N-glycan Processing Protein Phosphopantetheinylation Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Interconversion of nucleotide di- and triphosphates G1/S-Specific Transcription Transcriptional Regulation by E2F6	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Maturation of spike protein N-Glycan antennae elongation
Drugs		Cladribine Imexon Gallium nitrate Motexafin gadolinium GTI 2040
Diseases
GWAS		Kidney function decline traits ( 25493955) Prostate cancer ( 23535732)	Bipolar disorder ( 21926972 31043756 21738484) Idiopathic inflammatory myopathy ( 26362759) Left ventricular obstructive tract defect (inherited effect) ( 28468790)
Interacting Genes		9 interacting genes: CDH1 CDK1 DNM1L KAT5 PLK3 RRM1 RRM2B SDCBP TP53
Entrez ID		6241	11320
HPRD ID		01587	06860
Ensembl ID		ENSG00000171848	ENSG00000071073
Uniprot IDs		P31350	Q9UM21
PDB IDs		2UW2 3OLJ 3VPM 3VPN 3VPO
Enriched GO Terms of Interacting Partners?
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