BDKRB2 and MPI

Data Source:
BioGRID (two hybrid)

		BDKRB2	MPI
Description		bradykinin receptor B2	mannose phosphate isomerase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Intracellular Membrane-bounded Organelle	Cytosol Extracellular Exosome
	Molecular Function	Protease Binding Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Type 1 Angiotensin Receptor Binding Protein Heterodimerization Activity	Mannose-6-phosphate Isomerase Activity Zinc Ion Binding
	Biological Process	Smooth Muscle Contraction Inflammatory Response Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Circulation Response To Salt Stress Regulation Of Vasoconstriction Negative Regulation Of Peptidyl-serine Phosphorylation Vasoconstriction Vasodilation Regulation Of Vascular Permeability Arachidonic Acid Secretion Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator	Cell Wall Mannoprotein Biosynthetic Process Protein Glycosylation GDP-mannose Biosynthetic Process Mannose To Fructose-6-phosphate Metabolic Process
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Defective MPI causes MPI-CDG (CDG-1b) Synthesis of GDP-mannose
Drugs		Anatibant Icatibant Labradimil
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS		Cerebrospinal fluid AB1-42 levels ( 28247064) Corneal astigmatism ( 30306274) Gout ( 22179738) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821) Mumps ( 28928442) Subcutaneous adipose tissue ( 26480920)	Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mean arterial pressure ( 27618448) Red cell distribution width ( 32888494) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		33 interacting genes: AATK ACE AGTR1 AP2M1 CD81 CD82 CLCA4 EFS GNA11 GRK2 GRK3 GRK4 GRK5 GRK6 HERC2 INF2 MPI NIF3L1 NOS1 NOS3 PEX16 PRKCD PTPN11 SLC2A8 SLC35A4 SPG7 SPNS1 SYNE1 SYNGR2 TMEM11 TMEM70 TPI1 USP4	3 interacting genes: APP BDKRB2 SUMO2
Entrez ID		624	4351
HPRD ID		00213	01108
Ensembl ID		ENSG00000168398	ENSG00000178802
Uniprot IDs		P30411	B4DW50 F5GX71 H3BPB8 H3BPP3 P34949 Q8NHZ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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