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RPS8 and DLG3
Data Source:
BioGRID
(two hybrid)
RPS8
DLG3
Description
ribosomal protein S8
discs large MAGUK scaffold protein 3
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Endoplasmic Reticulum
Cytosol
Focal Adhesion
Membrane
Cytosolic Small Ribosomal Subunit
Extracellular Exosome
Ribonucleoprotein Complex
Extracellular Space
Cytosol
Plasma Membrane
Ionotropic Glutamate Receptor Complex
Basolateral Plasma Membrane
Cell Junction
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Protein Binding
Kinase Binding
Phosphatase Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Translation
Translational Initiation
SRP-dependent Cotranslational Protein Targeting To Membrane
Viral Transcription
MAPK Cascade
Negative Regulation Of Cell Population Proliferation
Embryo Development
Negative Regulation Of Phosphatase Activity
Receptor Clustering
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Positive Regulation Of Protein Tyrosine Kinase Activity
Receptor Localization To Synapse
Cell-cell Adhesion
Regulation Of NMDA Receptor Activity
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Unblocking of NMDA receptors, glutamate binding and activation
Unblocking of NMDA receptors, glutamate binding and activation
Ras activation upon Ca2+ influx through NMDA receptor
NrCAM interactions
Activation of Ca-permeable Kainate Receptor
RAF/MAP kinase cascade
Neurexins and neuroligins
Neurexins and neuroligins
Synaptic adhesion-like molecules
Assembly and cell surface presentation of NMDA receptors
Negative regulation of NMDA receptor-mediated neuronal transmission
Long-term potentiation
Drugs
Artenimol
Diseases
Non-syndromic X-linked mental retardation
GWAS
Mean platelet volume (
32888494
)
Interacting Genes
7 interacting genes:
CALM1
DLG2
DLG3
DUX4
NDRG1
RPS4X
SIRPA
48 interacting genes:
ABCA1
ADGRL1
APC
ATP2B4
CACNG2
CALM1
CNKSR2
CRIPT
DHRS11
DLG1
DLG4
DLGAP1
DLGAP2
DLGAP3
DLGAP4
EIF4H
ERBB4
EXOC4
EXOC7
GDA
GLS2
GRIK2
GRIN1
GRIN2A
GRIN2B
GRIN2C
GUCY1A2
KCNA4
KCNJ12
KCNJ2
KDELR1
KHDRBS1
KIF1B
LIN7A
LRP2
MAPK12
NLGN1
NLGN2
NLGN3
OSBP2
PLEKHA2
PTK2B
RPS8
SCN4A
SCN5A
SEMA4C
SYNGAP1
VTN
Entrez ID
6202
1741
HPRD ID
15969
02177
Ensembl ID
ENSG00000142937
ENSG00000082458
Uniprot IDs
P62241
Q5JR94
Q59FY1
Q92796
PDB IDs
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6EK0
6FEC
6G18
6G4S
6G4W
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBW
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOK
6ZON
6ZP4
6ZVH
6ZVJ
7A09
7K5I
1UM7
2FE5
2I1N
Enriched GO Terms of Interacting Partners
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