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RPL15 and SPP1
Data Source:
BioGRID
(two hybrid)
RPL15
SPP1
Description
ribosomal protein L15
secreted phosphoprotein 1
Image
GO Annotations
Cellular Component
Nucleus
Cytosol
Ribosome
Membrane
Cytosolic Large Ribosomal Subunit
A Band
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Golgi Apparatus
Cell Projection
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Cadherin Binding
Cytokine Activity
Integrin Binding
Protein Binding
Extracellular Matrix Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Cytoplasmic Translation
Translation
Translational Initiation
SRP-dependent Cotranslational Protein Targeting To Membrane
Viral Transcription
Response To Ethanol
Osteoblast Differentiation
Androgen Catabolic Process
Inflammatory Response
Cell Adhesion
Signal Transduction
Embryo Implantation
Extracellular Matrix Organization
Biomineral Tissue Development
Response To Vitamin D
Post-translational Protein Modification
Cellular Protein Metabolic Process
Positive Regulation Of Bone Resorption
Positive Regulation Of Transcription, DNA-templated
Decidualization
Response To Steroid Hormone
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Cellular Response To Testosterone Stimulus
Positive Regulation Of Estradiol Secretion
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Degradation of the extracellular matrix
Signaling by PDGF
Integrin cell surface interactions
Integrin cell surface interactions
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
RUNX3 Regulates Immune Response and Cell Migration
Post-translational protein phosphorylation
Drugs
(S)-3-phenyllactic acid
Anisomycin
Puromycin
Diseases
GWAS
Acne (severe) (
24927181
)
Extremely high intelligence (
29520040
)
Intelligence (MTAG) (
29326435
)
Blood protein levels (
30072576
)
Dental caries (
23064961
)
Urate levels (
31578528
)
Interacting Genes
7 interacting genes:
ARRB1
COPS6
DUX4
IL7R
MEOX2
SPP1
YWHAQ
97 interacting genes:
ABCF3
ACP5
AFF4
AMOTL2
APOA1
ATP2A2
ATP5PB
BAG6
BRD3
C1RL
C2orf50
CACNG4
CALM1
CC2D1B
CCR8
CD44
CEP162
CHD1
CISD2
CMTM3
COMMD1
COPS5
CSNK2A1
CSNK2A2
CTNNBL1
CYB5R3
DCX
DNAJB1
DNTTIP2
DRD2
DSEL
EEF1A1
EIF3K
EPAS1
ERBB2
F2
FTH1
GET3
GRIPAP1
HBA2
HMGN1
IGFBP5
ITGA5
ITGA9
ITGAV
ITGB1
ITGB5
KCNIP1
LRRC4
MAP1A
MAP1B
MARCKS
MEOX2
MMP3
MMP7
MPPED1
MRPL23
NACA
NCKAP1
NCS1
NCSTN
PDLIM7
PEMT
PEPD
PLD3
PRKACB
PRKCA
PRKG1
PTGER4
RANBP9
RAPGEF2
RBBP6
RIMS4
RPL13
RPL15
RPL5
RPS13
SEC24C
SGTA
SGTB
SLC22A1
SLC39A6
SNAPIN
SSB
STAU1
STK39
TBC1D8
TMEM168
TMEM30A
TPT1
TTC1
TUBB
UBQLN4
USP42
USP8
ZNF638
ZNF804A
Entrez ID
6138
6696
HPRD ID
16043
01325
Ensembl ID
ENSG00000174748
ENSG00000118785
Uniprot IDs
A0A024R2Q4
P61313
A0A024RDE2
A0A024RDE6
A0A024RDJ0
B7Z351
P10451
Q3LGB0
PDB IDs
4UG0
4V6X
5AJ0
5LKS
5T2C
6EK0
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
3CXD
3DSF
Enriched GO Terms of Interacting Partners
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