TNFRSF17 and CMTM7

Data Source:
BioGRID (two hybrid)

		TNFRSF17	CMTM7
Description		TNF receptor superfamily member 17	CKLF like MARVEL transmembrane domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endomembrane System Integral Component Of Membrane	Extracellular Space Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity	Cytokine Activity Protein Binding
	Biological Process	Adaptive Immune Response Lymphocyte Homeostasis Signal Transduction Multicellular Organism Development Tumor Necrosis Factor-mediated Signaling Pathway	B-1a B Cell Differentiation Chemotaxis Signal Transduction
Pathways		TNFs bind their physiological receptors
Drugs		Belantamab mafodotin
Diseases
GWAS		Blood protein levels ( 30072576) Phenylephrine infusion rate during anesthesia ( 31455332) QT interval ( 19305408) Testicular germ cell tumor ( 26503584)	Copper levels ( 26025379) Hallux valgus ( 32131869) IgM levels ( 28628107) Metabolite levels ( 23823483) Mortality in heart failure ( 20400778) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		8 interacting genes: CMTM7 PEX16 TMBIM6 TNFSF13 TNFSF13B TRAF1 TRAF2 TRAF3	47 interacting genes: ADTRP AGER AQP6 ARL13B B3GAT1 BIK BSCL2 CD74 CD79A CLSTN3 CREB3L1 DAGLA DNAJC1 ELOVL4 FAM174A FAM209A FFAR2 FRMD3 GGT7 GORAB HAS3 HIBADH HSD17B13 LDLRAD1 LHFPL5 LMNA MS4A4A MUC1 PAGE1 PIANP PSMD6 RETREG3 SDC3 SHISA3 SLC14A2 SLC30A8 SSMEM1 STX1A TCTA TEX29 THAP4 TMEM106C TMEM174 TMEM31 TMPRSS2 TMX2 TNFRSF17
Entrez ID		608	112616
HPRD ID		00144	06988
Ensembl ID		ENSG00000048462	ENSG00000153551
Uniprot IDs		Q02223	F8WDZ3 Q96FZ5
PDB IDs		1OQD 1XU2 2KN1 4ZFO 6J7W
Enriched GO Terms of Interacting Partners?
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