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RGS7 and PKD1
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
RGS7
PKD1
Description
regulator of G protein signaling 7
polycystin 1, transient receptor potential channel interacting
Image
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Golgi Membrane
Polycystin Complex
Nucleus
Cytoplasm
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Cilium
Cell Surface
Integral Component Of Membrane
Basolateral Plasma Membrane
Lateral Plasma Membrane
Golgi-associated Vesicle Membrane
Motile Cilium
Cation Channel Complex
Calcium Channel Complex
Ciliary Membrane
Extracellular Exosome
Molecular Function
GTPase Activity
GTPase Activator Activity
G-protein Beta-subunit Binding
Calcium Channel Activity
Protein Binding
Protein Kinase Binding
Protein Domain Specific Binding
Carbohydrate Binding
Wnt-activated Receptor Activity
Ion Channel Binding
Biological Process
Protein Folding
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Intracellular Signal Transduction
Positive Regulation Of GTPase Activity
Cartilage Condensation
In Utero Embryonic Development
Kidney Development
Liver Development
Embryonic Placenta Development
Protein Export From Nucleus
Cell Cycle Arrest
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Cell-matrix Adhesion
Calcium-independent Cell-matrix Adhesion
Positive Regulation Of Cytosolic Calcium Ion Concentration
Receptor Signaling Pathway Via JAK-STAT
Heart Development
Anatomical Structure Morphogenesis
Wnt Signaling Pathway
Peptidyl-serine Phosphorylation
Spinal Cord Development
Neural Tube Development
Establishment Of Cell Polarity
Regulation Of Cell Adhesion
Positive Regulation Of Protein Binding
Response To Fluid Shear Stress
Lymph Vessel Morphogenesis
Cytoplasmic Sequestering Of Transcription Factor
Skin Development
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Digestive Tract Development
Branching Morphogenesis Of An Epithelial Tube
Genitalia Development
Detection Of Mechanical Stimulus
Cartilage Development
Protein Heterotetramerization
Regulation Of Mitotic Spindle Organization
Lung Epithelium Development
Placenta Blood Vessel Development
Regulation Of Proteasomal Protein Catabolic Process
Calcium Ion Transmembrane Transport
Mesonephric Tubule Development
Mesonephric Duct Development
Metanephric Collecting Duct Development
Metanephric Ascending Thin Limb Development
Metanephric Proximal Tubule Development
Metanephric Distal Tubule Morphogenesis
Cell-cell Signaling By Wnt
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
G alpha (i) signalling events
G alpha (i) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
VxPx cargo-targeting to cilium
VxPx cargo-targeting to cilium
Drugs
Diseases
Polycystic kidney disease
GWAS
Chronotype (
30696823
)
Diastolic blood pressure (
29208002
)
Ischemic stroke (cardioembolic) (
29531354
)
Longevity (90 years and older) (
25199915
)
Major depressive disorder (
27479909
)
Obesity-related traits (
23251661
)
Post bronchodilator FEV1 (
26634245
)
Western dietary pattern (
28644415
)
Appendicular lean mass (
33097823
)
Estimated glomerular filtration rate (
31451708
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Heel bone mineral density (
30598549
)
Height (
28552196
)
High light scatter reticulocyte count (
32888494
)
Major depressive disorder (
29317602
)
Neutrophil count (
32888494
)
Systolic blood pressure (
30578418
)
Interacting Genes
16 interacting genes:
CHRM1
CHRM2
CHRM3
CHRM5
GNAI1
GNAI3
GNAO1
GNAQ
GNAZ
GNB5
MSX1
PKD1
PRKCA
SNAPIN
YWHAB
YWHAQ
30 interacting genes:
ACTN1
ATF7IP
BCAR1
CDH1
COL1A1
COL2A1
CTNNA1
CTNNB1
DES
FN1
HDAC9
JAK2
JUP
KRT18
KRT8
LTB4R2
MARK2
NCF1
NCK2
PIP5K1C
PKD2
PTK2
PTPRG
PXN
RGS7
SIAH1
SRC
TLN1
VCL
VIM
Entrez ID
6000
5310
HPRD ID
03948
03203
Ensembl ID
ENSG00000182901
ENSG00000008710
Uniprot IDs
B7Z223
B7Z257
P49802
P98161
PDB IDs
2A72
2D9J
1B4R
6A70
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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