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BCL2L1 and BNIP3
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
BCL2L1
BNIP3
Description
BCL2 like 1
BCL2 interacting protein 3
Image
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Mitochondrial Inner Membrane
Mitochondrial Matrix
Centrosome
Cytosol
Integral Component Of Membrane
Synaptic Vesicle Membrane
Nuclear Membrane
Bcl-2 Family Protein Complex
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Postsynaptic Density
Dendrite
Integral Component Of Mitochondrial Outer Membrane
Mitochondrial Membrane
Molecular Function
Protein Binding
Protein Kinase Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
BH3 Domain Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
GTPase Binding
Biological Process
Release Of Cytochrome C From Mitochondria
Endocytosis
Mitotic Cell Cycle Checkpoint
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Apoptotic Mitochondrial Changes
Suppression By Virus Of Host Apoptotic Process
Cytokine-mediated Signaling Pathway
Regulation Of Cytokinesis
Response To Cytokine
Negative Regulation Of Apoptotic Process
Regulation Of Mitochondrial Membrane Permeability
Defense Response To Virus
Regulation Of Mitochondrial Membrane Potential
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Execution Phase Of Apoptosis
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Protein Localization To Plasma Membrane
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Autophagy Of Mitochondrion
Response To Hypoxia
Apoptotic Process
Cell Death
Response To Bacterium
Positive Regulation Of Autophagy
Negative Regulation Of Mitochondrial Fusion
Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Mitochondrial Membrane Potential
Positive Regulation Of Necrotic Cell Death
Viral Process
Positive Regulation Of Macroautophagy
Cerebral Cortex Development
Mitochondrial Protein Catabolic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Protein-containing Complex Disassembly
Mitochondrial Fragmentation Involved In Apoptotic Process
Negative Regulation Of Membrane Potential
Regulation Of Mitochondrial Membrane Permeability
Autophagic Cell Death
Response To Axon Injury
Oligodendrocyte Differentiation
Brown Fat Cell Differentiation
Neuron Apoptotic Process
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Defense Response To Virus
Response To Hyperoxia
Negative Regulation Of Cell Death
Cellular Response To Hydrogen Peroxide
Cellular Response To Mechanical Stimulus
Cellular Response To Cobalt Ion
Cellular Response To Hypoxia
Reactive Oxygen Species Metabolic Process
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Response To Oxygen-glucose Deprivation
Mitochondrial Outer Membrane Permeabilization
Granzyme-mediated Programmed Cell Death Signaling Pathway
Toxin Transport
Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Positive Regulation Of Autophagy Of Mitochondrion
Regulation Of Aerobic Respiration
Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Interleukin-4 and Interleukin-13 signaling
The NLRP1 inflammasome
RAS processing
STAT5 activation downstream of FLT3 ITD mutants
Drugs
4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID
Isosorbide
Gossypol
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Monocyte percentage of white cells (
27863252
)
Mosaic loss of chromosome Y (Y chromosome dosage) (
31624269
)
Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder (
26184070
)
Platelet count (
32888494
27863252
)
Plateletcrit (
32888494
27863252
)
Prudent dietary pattern (
28644415
)
Putamen volume (
29147026
)
Subcortical brain region volumes (
25607358
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Metabolite levels (
23823483
)
Interacting Genes
110 interacting genes:
ACTB
AKT1
ANTXR1
APAF1
AURKA
AVEN
BAD
BAG1
BAK1
BAX
BBC3
BCAP31
BCL2
BCL2L10
BCL2L11
BCL2L12
BCL2L14
BCLAF1
BECN1
BID
BIK
BLK
BMF
BNIP1
BNIP3
BNIP3L
BNIP5
BNIPL
C10orf67
CAPN1
CASP1
CASP8
CASP9
CDKN2A
CFLAR
CHEK1
CREB3
CRYAA
CRYAB
CYCS
DOCK7
EDRF1
ELOVL4
ERGIC3
FBP1
FKBP8
G0S2
GLOD4
GNLY
GOLM1
GORAB
GSK3A
GSK3B
HNRNPA1
HRK
IKZF3
IRS1
IRS2
LARP1
MAPK14
MAPK8
MAPK9
MAPKAPK2
MCL1
METTL23
MOAP1
MTIF3
MTNR1B
MTOR
NLRP1
PARK7
PDIA4
PLD3
PLK1
PLK3
PMAIP1
PPHLN1
PPP1CA
PRKN
PSEN1
PSEN2
PTN
RAD9A
RAF1
RBM5
REEP4
RHBDD2
RIC3
RNF183
RNF4
RTN1
RTN4
RYR3
SIVA1
SNCA
SPNS1
TLE1
TMBIM6
TMEM50B
TP53
TP53BP2
TPT1
UBE2I
UBR1
UHRF2
VAC14
VDAC1
ZFYVE1
ZHX1
ZNF219
70 interacting genes:
AGTR1
AMIGO1
ARL13B
BCL2
BCL2L1
BCL2L2
BIK
BNIP2
BNIP3L
CD3E
CD47
CLDN9
CLEC7A
CLN8
CMTM5
CREB3
CREB3L1
EBAG9
EBP
ELOVL4
ERGIC3
FAM209A
FAM241B
FATE1
FFAR2
FXYD6-FXYD2
GPR152
GPR37
GPR42
HIF1A
HIVEP1
HPN
HTR2B
IFNGR2
JAGN1
KTN1
LDLRAD1
LMNA
MALL
MAP1LC3B
MFSD14B
MS4A3
NCBP1
OPA1
PLP2
PPTC7
REEP2
RHEB
RNASEK
RNF24
RPRM
SCN3B
SEC22A
SEC23A
SLC31A2
SLC35B1
SLC6A17
SMIM3
SPACA1
TGM2
TLCD4
TM4SF18
TMEM101
TMEM106C
TMEM11
TMEM205
TMPRSS2
TMX2
TNMD
ZDHHC15
Entrez ID
598
664
HPRD ID
02497
04482
Ensembl ID
ENSG00000171552
ENSG00000176171
Uniprot IDs
A0A0S2Z3C5
Q07817
Q5TE63
Q12983
Q6NVY4
PDB IDs
1BXL
1G5J
1LXL
1MAZ
1R2D
1R2E
1R2G
1R2H
1R2I
1YSG
1YSI
1YSN
2B48
2LP8
2LPC
2M03
2M04
2ME8
2ME9
2MEJ
2O1Y
2O2M
2O2N
2P1L
2PON
2YJ1
2YQ6
2YQ7
2YXJ
3CVA
3FDL
3FDM
3INQ
3IO8
3PL7
3QKD
3R85
3SP7
3SPF
3WIZ
3ZK6
3ZLN
3ZLO
3ZLR
4A1U
4A1W
4AQ3
4BPK
4C52
4C5D
4CIN
4EHR
4HNJ
4IEH
4PPI
4QVE
4QVF
4QVX
4TUH
4Z9V
5AGW
5AGX
5B1Z
5C3G
5FMJ
5FMK
5VAY
5VX3
6BF2
6DCN
6DCO
6F46
6HJL
6IJQ
6O0K
6O0L
6O0M
6O0O
6O0P
6RNU
6ST2
6VWC
6X7I
6ZHC
7CA4
2J5D
2KA1
2KA2
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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