RBM4 and DDX17

Data Source:
BioGRID (two hybrid, two hybrid)

		RBM4	DDX17
Description		RNA binding motif protein 4	DEAD-box helicase 17
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding Cyclin Binding MiRNA Binding Pre-mRNA Intronic Binding Pre-mRNA Intronic Pyrimidine-rich Binding	Transcription Coactivator Activity RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Cap-independent Translational Initiation IRES-dependent Translational Initiation Of Linear MRNA RNA Processing Negative Regulation Of Translation Cell Differentiation Negative Regulation Of Translation In Response To Stress MiRNA Mediated Inhibition Of Translation Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Translational Initiation Response To Arsenic-containing Substance Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Muscle Cell Differentiation Circadian Regulation Of Translation	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II RRNA Processing RNA Processing MiRNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Gene Silencing By RNA Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Circadian Clock	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Menopause (age at onset) ( 26414677) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		95 interacting genes: AQR CCNA1 CDK2 DDX17 DDX5 DHX9 ESS2 HNRNPF HNRNPH2 HNRNPH3 HNRNPK HNRNPM HNRNPUL1 KLHL41 LRP2BP MAPK8IP2 MIR1-1 MIR1-2 MIR106A MIR106B MIR10B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-2 MIR17 MIR199A1 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PABPC1 PRPF31 PTBP2 PTEN RBM10 RBM22 RBM23 RBM42 RBM7 SF1 SF3B4 SMAD5 SNRPC STEEP1 TRIB3 U2AF2	38 interacting genes: APBB1 APP BYSL CCDC187 CREBBP CSNK2A1 DDX5 DDX6 ESR1 FBL FXR2 GAS8 GRB2 HDAC1 HNRNPH1 HNRNPH3 HNRNPK LNX1 NCOA1 NCOA2 NCOA3 PIN1 PTK6 PTPRD RBM10 RBM14 RBM15 RBM4 RBM5 SF1 SF3B4 SNRNP70 SORBS3 SREK1 SUMO2 WBP11 WBP2 YWHAG
Entrez ID		5936	10521
HPRD ID		03982	10532
Ensembl ID		ENSG00000173933	ENSG00000100201
Uniprot IDs		Q9BWF3	Q59F66 Q92841
PDB IDs		2DNQ	6UV0 6UV1 6UV2 6UV3 6UV4
Enriched GO Terms of Interacting Partners?
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