UBL5 and NFYA

Data Source:
BioGRID (two hybrid)

		UBL5	NFYA
Description		ubiquitin like 5	nuclear transcription factor Y subunit alpha
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Protein Tag	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cellular Protein Modification Process Positive Regulation Of Protein Targeting To Mitochondrion	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Rhythmic Process
Pathways			PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS		Sleep duration ( 30531941) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Mean spheric corpuscular volume ( 32888494) White blood cell count ( 27863252)
Interacting Genes		48 interacting genes: BEND7 BIN3 C1QTNF1 CCDC196 CCDC28B CERCAM CLK1 CLK2 CLK4 CTAG1A CTAG1B FAM50B FANCI GCSAML HESX1 HID1 HMGXB4 HOXA1 HSPB2 KRTAP10-8 KRTAP13-3 LENG1 MBD3L1 NCOA5 NFYA NME4 NRIP3 PAX4 PHACTR3 PINX1 PRMT8 PSME2 SART1 SEPTIN2 SERTAD3 SF1 SMCP SPANXB1 SPATC1L TEX35 THAP3 TLE5 TRIM27 TRIM39 WASHC1 ZFP41 ZNF124 ZNF618	48 interacting genes: APP APPBP2 ATF6 ATF6B ATXN1 BANP BRCA1 CCNA2 CDC25A CDK2 CDKN1A CEBPA CSNK2A1 DVL3 E2F6 ELF1 GTF2A1 HMGA1 JUN KPNB1 LUC7L2 NFYB NFYC NR5A1 PAPOLG POGZ POU2F1 POU3F2 PWP1 QRICH1 SP1 SPI1 SREBF2 SRF SRSF1 TAF11 TAF12 TAF6 TCAF1 TP53 UBL5 USF1 USF2 VEZF1 ZC3H10 ZHX1 ZHX2 ZHX3
Entrez ID		59286	4800
HPRD ID		06028	01793
Ensembl ID		ENSG00000198258	ENSG00000001167
Uniprot IDs		A0A024R7B0 Q9BZL1	A0A024RD22 P23511
PDB IDs		1P0R 4PYU 6AHD	4AWL 6QMP 6QMQ 6QMS
Enriched GO Terms of Interacting Partners?
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