RAB5C and HOXB13

Data Source:
BioGRID (affinity chromatography technology)

		RAB5C	HOXB13
Description		RAB5C, member RAS oncogene family	homeobox B13
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GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Lipid Droplet Plasma Membrane Endomembrane System Endocytic Vesicle Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome	Chromatin Nucleoplasm Transcription Regulator Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Intracellular Protein Transport Endocytosis Regulation Of Endocytosis Neutrophil Degranulation Plasma Membrane To Endosome Transport	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of Transcription By RNA Polymerase II Epidermis Development Response To Wounding Response To Testosterone Regulation Of Growth Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development
Pathways		Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422 26561523) Mean corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737) White blood cell count ( 32888494)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Prostate cancer ( 23104005 23535732)
Interacting Genes		15 interacting genes: ALS2CL APP APPL2 EEA1 ERBB2 GLP1R HRAS INCA1 RABAC1 RBSN RIN2 RIN3 SGSM3 TBC1D15 TBC1D17	7 interacting genes: ALX4 ELK1 HOXD4 IRF4 MEIS1 POU2F1 ZNF490
Entrez ID		5878	10481
HPRD ID		04947	05210
Ensembl ID		ENSG00000108774	ENSG00000159184
Uniprot IDs		A0A024R1U4 P51148	Q4KR72 Q92826
PDB IDs		4KYI	2CRA 5EDN 5EEA 5EF6 5EG0 5EGO 5NO6
Enriched GO Terms of Interacting Partners?
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