ENOPH1 and RAB10

Data Source:
BioGRID (two hybrid)

		ENOPH1	RAB10
Description		enolase-phosphatase 1	RAB10, member RAS oncogene family
Image
GO Annotations	Cellular Component	Nucleus Cytosol	Golgi Membrane Exocyst Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Synaptic Vesicle Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network
	Molecular Function	Magnesium Ion Binding Protein Binding 2,3-diketo-5-methylthiopentyl-1-phosphate Enolase Activity 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate Phosphatase Activity Acireductone Synthase Activity	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Dephosphorylation L-methionine Salvage From S-adenosylmethionine L-methionine Salvage From Methylthioadenosine	Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Axonogenesis Protein Secretion Vesicle-mediated Transport Endosomal Transport Regulation Of Exocytosis Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Neutrophil Degranulation Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane
Pathways		Methionine salvage pathway	Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs		2-OXOHEPTYLPHOSPHONIC ACID
Diseases
GWAS			Apolipoprotein B levels ( 32203549) Immune response to smallpox vaccine (IL-6) ( 22542470) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000) Platelet distribution width ( 32888494)
Interacting Genes		6 interacting genes: ERBB3 RAB10 RNF41 RPS27 TSC22D2 ZNF280A	9 interacting genes: APP ENOPH1 EVI5L MICAL1 MTNR1A PPBP RABIF RIMS1 SEPTIN9
Entrez ID		58478	10890
HPRD ID		17467	06692
Ensembl ID		ENSG00000145293	ENSG00000084733
Uniprot IDs		D6RA00 Q9UHY7	P61026
PDB IDs		1YNS 1ZS9	5LPN 5SZJ
Enriched GO Terms of Interacting Partners?
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