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TRIB3 and PPP1R32
Data Source:
BioGRID
(two hybrid)
TRIB3
PPP1R32
Description
tribbles pseudokinase 3
protein phosphatase 1 regulatory subunit 32
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Ciliary Basal Body
Molecular Function
Transcription Corepressor Activity
Protein Kinase Inhibitor Activity
Protein Binding
ATP Binding
Kinase Activity
Protein Kinase Binding
Mitogen-activated Protein Kinase Kinase Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-protein Transferase Regulator Activity
Protein Binding
Phosphatase Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Negative Regulation Of Protein Kinase Activity
Regulation Of Autophagy
Regulation Of Glucose Transmembrane Transport
Regulation Of Lipid Metabolic Process
Positive Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Response To Endoplasmic Reticulum Stress
Regulation Of MAP Kinase Activity
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Protein Kinase B Signaling
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways
PIP3 activates AKT signaling
Activation of AKT2
PPARA activates gene expression
Negative regulation of the PI3K/AKT network
CD28 dependent PI3K/Akt signaling
VEGFR2 mediated vascular permeability
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS
Information processing speed (
21130836
)
Logical memory (delayed recall) (
29274321
)
Logical memory (immediate recall) (
29274321
)
Spatial memory (
31596458
)
Interacting Genes
99 interacting genes:
AKAP8L
AKT1
AKT2
APOBEC3A
APOBEC3C
APP
ARMC7
ATF4
BAG3
BCL6
BFSP2
BMPR2
C21orf58
C22orf39
CBX8
CHAF1A
CLCNKA
COPS6
CTAG1A
CTAG1B
DDIT3
DPPA3
DTX2
EEF1G
EFEMP2
EPHB6
EXOSC5
FAAP20
FAM161A
FAM90A1
FBXO7
GDF9
GIT1
GLIS3
GPATCH2L
GRB2
HAT1
HDAC4
HLA-B
HNRNPF
HOXB5
HOXC8
IL16
INCA1
INO80B
IRX6
KANK2
KAT5
KLHL38
KRT26
LENG1
LMO2
LMO3
MDFI
MISP
OIP5
OSTF1
PADI4
PARD6B
PCSK5
PITX2
PKNOX2
PML
PPP1R26
PPP1R32
PRKAB2
PRMT5
PRR19
PSMA3
RARA
RBM4
RBM48
RELA
RIDA
RPGRIP1
RPSA
SAMD11
SAXO1
SCNM1
SETDB1
SHFL
SNRPC
SPAG8
SPG21
SQSTM1
SUOX
TCF19
TEKT3
TEKT4
TLE5
TRIM55
TRIM63
TTC23
TWIST1
UBTD2
USP20
UTP23
ZNF417
ZNF587
72 interacting genes:
AKAP8L
ALS2CL
APP
ATN1
ATPAF2
B9D2
BAG4
BCAS2
C10orf55
CATSPER1
CCDC57
COG6
COX5B
CSTF2
CTDSP1
CYSRT1
DTX2
FAM168B
FHL2
FHL3
FHL5
FKBP6
FRS3
GOLGA2
HGS
HNRNPH1
HOMER3
HOXA1
HSF2BP
INCA1
KCTD9
KPRP
KRT31
KRTAP13-2
KRTAP19-5
KRTAP19-6
KRTAP3-1
KRTAP3-2
KRTAP6-2
KRTAP6-3
KRTAP8-1
LASP1
LMO2
LMO4
METTL27
MYO15B
OIP5
OTUD7B
PFDN5
PLA2G10
PLEKHG4
PLEKHN1
PPP1CA
PPP1CC
PRDM14
PRKAA2
QARS1
RBM11
RFX6
RIMBP3C
SLAIN1
TEKT4
TFG
TGM7
TRAF1
TRAF2
TRIB3
TSC1
UNKL
VMAC
WWOX
ZMYND12
Entrez ID
57761
220004
HPRD ID
09836
16933
Ensembl ID
ENSG00000101255
ENSG00000162148
Uniprot IDs
B4DMM9
J3KR25
Q96RU7
G3F4G3
Q7Z5V6
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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