Description |
protein tyrosine phosphatase non-receptor type 1 |
CDC like kinase 1 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- 3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid
- 2-{[4-(2-Acetylamino-2-pentylcarbamoyl-ethyl)-naphthalen-1-YL]-oxalyl-amino}-benzoic acid
- 5-(2-Fluoro-5-{(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]-1-propen-1-yl}phenyl)-1,2-oxazole-3-carboxylic acid
- 2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Thiopyran-3-Carboxylic Acid
- 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid (4-Sulfamoyl-Phenyl)-Amide
- [[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid,
- {4-[(2S)-2-({[(1S)-1-Carboxy-2-phenylethyl]carbamoyl}amino)-3-oxo-3-(pentylamino)propyl]phenoxy}malonic acid
- Compound 19
- 3-(4-{2-[2-(2-bromo-acetylamino)-ethyldisulfanyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-pyrazine-2-carboxylic acid
- 2-(Oxalyl-Amino)-Benzoic Acid
- {[2-(1h-1,2,3-Benzotriazol-1-Yl)-2-(3,4-Difluorophenyl)Propane-1,3-Diyl]Bis[4,1-Phenylene(Difluoromethylene)]}Bis(Phosphonic Acid)
- Novo Nordisk a/S Compound
- N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide
- 7-(1,1-Dioxo-1h-Benzo[D]Isothiazol-3-Yloxymethyl)-2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid
- PNU177836
- 2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid
- {[7-(Difluoro-Phosphono-Methyl)-Naphthalen-2-Yl]-Difluoro-Methyl}-Phosphonic Acid
- 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid [4-(Thiazol-2-Ylsulfamoyl)-Phenyl]-Amide
- (4S)-5-[[(2S)-1-[[(2S)-1-Amino-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-4-benzamido-5-oxopentanoic acid
- 4-[[(2S)-1-[[6-[(1-Amino-1-oxo-3-sulfanylpropan-2-yl)amino]-6-oxohexyl]amino]-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[[2-[4-[difluoro(phosphono)methyl]phenyl]acetyl]amino]-4-oxobutanoic acid
- L-cysteic acid
- 2-(Oxalyl-Amino)-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid
- 4-Carbamoyl-4-{[6-(Difluoro-Phosphono-Methyl)-Naphthalene-2-Carbonyl]-Amino}-Butyric Acid
- Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid
- 6-(Oxalyl-Amino)-1h-Indole-5-Carboxylic Acid
- 2-[{4-[(2S)-2-{[(Allyloxy)carbonyl]amino}-3-({4-[3-hydroxy-2-(methoxycarbonyl)phenoxy]butyl}amino)-3-oxopropyl]phenyl}(carboxycarbonyl)amino]benzoic acid
- 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid Dimethylamide
- [(4-{4-[4-(Difluoro-Phosphono-Methyl)-Phenyl]-Butyl}-Phenyl)-Difluoro-Methyl]-Phosphonic Acid
- {4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid
- N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide
- 1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID
- ISIS 113715
- Trodusquemine
- Ertiprotafib
- 4-BROMO-3-(CARBOXYMETHOXY)-5-[3-(CYCLOHEXYLAMINO)PHENYL]THIOPHENE-2-CARBOXYLIC ACID
- [(3S)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid
- 4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID
- 5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
- 4-BROMO-3-(CARBOXYMETHOXY)-5-(4-HYDROXYPHENYL)THIOPHENE-2-CARBOXYLIC ACID
- [{2-bromo-4-[(2R)-3-oxo-2,3-diphenylpropyl]phenyl}(difluoro)methyl]phosphonic acid
- 5-[3-(BENZYLAMINO)PHENYL]-4-BROMO-3-(CARBOXYMETHOXY)THIOPHENE-2-CARBOXYLIC ACID
- 2-[(7-HYDROXY-NAPHTHALEN-1-YL)-OXALYL-AMINO]-BENZOIC ACID
- 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
- 4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN
- N-ACETYL-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDE
- [(3R)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid
- 5-(3-HYDROXYPHENYL)ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE
- 5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLIC ACID
- ISOTHIAZOLIDINONE ANALOG
- 4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid
- p-Benzoyl-L-phenylalanine
- 6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBOXYLIC ACID
- (3R)-METHYLCARBAMOYL-7-SULFOAMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER
- 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
- 1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE
- (4-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-methoxy-3-oxopropyl}phenyl)methaneseleninic acid
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Diseases |
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GWAS |
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Interacting Genes |
66 interacting genes:
ACTN1
AGR3
AKT1
AQP6
ASS1
BCAR1
BCAS3
BCR
CAPN2
CASC3
CASZ1
CAV1
CCL5
CDH13
CDH2
CDK1
CLK1
CLK2
COP1
CRK
CSNK2A1
CSNK2A2
CTNNB1
DIRAS3
EGFR
ELOVL4
ESR1
FGFR1
GHR
GLRX
GRB2
GSK3B
IGF1R
INSR
IRS1
JAK2
KLK7
LAT
LRATD2
LTK
MAPK1
MRC2
NFKBIA
NTRK1
NTRK2
NTRK3
PDGFRB
PIAS1
PIGP
PIN1
RHOBTB2
RRAS2
SNAI1
SRC
STAM2
STAT3
STAT5A
STAT5B
THRSP
TIMMDC1
TMEM31
TMEM41A
TMEM86B
TRPV6
TYK2
VPS45
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166 interacting genes:
ABCA13
ACOX2
ANKFY1
ARHGEF12
ARPC4
ASL
ASXL3
ATP10A
ATP4A
BCLAF1
C1orf94
CDCP1
CDH23
CDK12
CELSR3
CENPE
CEP95
CFAP20DC
CFAP251
CKAP5
CLASRP
CLK2
COCH
CRNKL1
CTNND2
CUL3
CWC27
CYP46A1
DBR1
DENND4A
DNAJC13
DNAJC24
DOCK9
DPYD
DSC2
DVL3
ECE1
ELP6
ENO1
ERFE
FAM189A1
FAT1
FBF1
FHIP2B
GEMIN5
GOLM1
GRM6
GSDMB
H2BC12
HADH
HIVEP1
HNMT
HNRNPA0
HNRNPA1
HNRNPA3
HSP90AB2P
HSPBP1
HTATSF1
ICE1
IMPDH2
IP6K1
ITGA5
KATNA1
KHDRBS1
KIF14
KIF23
KRT8
KRTAP10-6
KRTAP10-7
LINS1
LMNA
LNX1
LUC7L3
MAP3K21
MAP7
MBP
MFHAS1
MFSD10
MICU3
MKRN2
MTBP
MTCL1
MYOM1
NCL
NCOR1
NF1
NPM1
NUP153
PATZ1
PDE9A
PHF3
PHLDB2
PIAS4
PIP4K2B
PKD1L1
PLAAT5
PLXDC2
PPFIBP2
PPHLN1
PPIG
PPP1CB
PRDX5
PRKDC
PRMT5
PRPF38A
PRPF4
PRPF4B
PTPN1
PTPN22
RAD21L1
RAPH1
RASL12
RBBP6
RBM15
RBM39
RBMX
REV1
RLF
RPL5
RPS4Y1
RPUSD3
SAFB
SAMD9L
SCARA3
SERPINI2
SF3B1
SFMBT2
SH2B2
SHROOM1
SLC35D3
SLFN5
SPEN
SPTBN4
SRPK1
SRPK2
SRRM1
SRRM2
SRRM4
SRSF1
SRSF10
SRSF3
SRSF5
SRSF6
SRSF7
SSBP3
STIP1
STK31
SVOP
TEX11
THRAP3
THY1
TJP2
TLN2
TMPO
TMPRSS2
TNIP2
TP53RK
TRA2B
UBL5
UNC13B
VWA7
YTHDC1
YWHAG
ZC3H13
ZMYND10
ZNF148
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Entrez ID |
5770 |
1195 |
HPRD ID |
01477 |
09058 |
Ensembl ID |
ENSG00000196396
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ENSG00000013441
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Uniprot IDs |
A8K3M3
B4DSN5
P18031
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P49759
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PDB IDs |
1A5Y
1AAX
1BZC
1BZH
1BZJ
1C83
1C84
1C85
1C86
1C87
1C88
1ECV
1EEN
1EEO
1G1F
1G1G
1G1H
1G7F
1G7G
1GFY
1I57
1JF7
1KAK
1KAV
1L8G
1LQF
1NL9
1NNY
1NO6
1NWE
1NWL
1NZ7
1OEM
1OEO
1OES
1OET
1OEU
1OEV
1ONY
1ONZ
1PA1
1PH0
1PTT
1PTU
1PTV
1PTY
1PXH
1PYN
1Q1M
1Q6J
1Q6M
1Q6N
1Q6P
1Q6S
1Q6T
1QXK
1SUG
1T48
1T49
1T4J
1WAX
1XBO
2AZR
2B07
2B4S
2BGD
2BGE
2CM2
2CM3
2CM7
2CM8
2CMA
2CMB
2CMC
2CNE
2CNF
2CNG
2CNH
2CNI
2F6F
2F6T
2F6V
2F6W
2F6Y
2F6Z
2F70
2F71
2FJM
2FJN
2H4G
2H4K
2HB1
2HNP
2HNQ
2NT7
2NTA
2QBP
2QBQ
2QBR
2QBS
2VEU
2VEV
2VEW
2VEX
2VEY
2ZMM
2ZN7
3A5J
3A5K
3CWE
3D9C
3EAX
3EB1
3EU0
3I7Z
3I80
3QKP
3QKQ
3SME
3ZMP
3ZMQ
3ZV2
4BJO
4I8N
4QAH
4QAP
4QBE
4QBW
4Y14
4ZRT
5K9V
5K9W
5KA0
5KA1
5KA2
5KA3
5KA4
5KA7
5KA8
5KA9
5KAA
5KAB
5KAC
5KAD
5QDE
5QDF
5QDG
5QDH
5QDI
5QDJ
5QDK
5QDL
5QDM
5QDN
5QDO
5QDP
5QDQ
5QDR
5QDS
5QDT
5QDU
5QDV
5QDW
5QDX
5QDY
5QDZ
5QE0
5QE1
5QE2
5QE3
5QE4
5QE5
5QE6
5QE7
5QE8
5QE9
5QEA
5QEB
5QEC
5QED
5QEE
5QEF
5QEG
5QEH
5QEI
5QEJ
5QEK
5QEL
5QEM
5QEN
5QEO
5QEP
5QEQ
5QER
5QES
5QET
5QEU
5QEV
5QEW
5QEX
5QEY
5QEZ
5QF0
5QF1
5QF2
5QF3
5QF4
5QF5
5QF6
5QF7
5QF8
5QF9
5QFA
5QFB
5QFC
5QFD
5QFE
5QFF
5QFG
5QFH
5QFI
5QFJ
5QFK
5QFL
5QFM
5QFN
5QFO
5QFP
5QFQ
5QFR
5QFS
5QFT
5QFU
5QFV
5QFW
5QFX
5QFY
5QFZ
5QG0
5QG1
5QG2
5QG3
5QG4
5QG5
5QG6
5QG7
5QG8
5QG9
5QGA
5QGB
5QGC
5QGD
5QGE
5QGF
5T19
6B8E
6B8T
6B8X
6B8Z
6B90
6B95
6BAI
6CWU
6CWV
6NTP
6OL4
6OLQ
6OLV
6OMY
6PFW
6PG0
6PGT
6PHA
6PHS
6PM8
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1Z57
2VAG
5J1V
5J1W
5X8I
6FT8
6FT9
6FYO
6G33
6I5H
6I5I
6I5K
6I5L
6KHD
6Q8K
6Q8P
6QTY
6R3D
6R6E
6R6X
6R8J
6RAA
6TW2
6YTA
6YTD
6YTE
6YTG
6YTI
6Z4Z
6Z50
6ZLN
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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