ZBTB26 and PPL

Data Source:
BioGRID (two hybrid)

		ZBTB26	PPL
Description		zinc finger and BTB domain containing 26	periplakin
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleoplasm	Cornified Envelope Cytoplasm Cytosol Cytoskeleton Intermediate Filament Plasma Membrane Membrane Desmosome Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cadherin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Biological_process	Response To Mechanical Stimulus Wound Healing Intermediate Filament Cytoskeleton Organization Cornification
Pathways			Formation of the cornified envelope Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)	Adult body size ( 32376654) Cancer ( 29299148) Diastolic blood pressure ( 28135244 27841878) Height ( 28552196) Lung cancer (asbestos exposure interaction) ( 22637743) Metabolite levels (HVA/MHPG ratio) ( 23319000) Mitochondrial DNA copy number (white blood cells) ( 30704525) Systolic blood pressure ( 27841878)
Interacting Genes		35 interacting genes: AXIN1 CARD10 CDC37 CDC7 CYP2W1 DAXX DVL3 EHHADH EIF6 GAS8 GIPC2 HMBOX1 L3MBTL2 LNX1 MORF4L1 MORF4L2 PBK PPL RAD23A RAD54L2 RNF4 SOX5 SUMO1 SUMO1P1 TRAF4 TRIM41 TSGA10 UBE2I ZBTB12 ZBTB34 ZBTB48 ZBTB6 ZBTB9 ZMYM5 ZNF408	43 interacting genes: ACTR5 AHCYL1 AKT1 ALAS1 C6orf141 CASP6 CEP57L1 COL17A1 DES EVPL HECTD3 IKZF1 ITSN1 KAZN KCTD21 KNSTRN KRT25 KRT39 KRT8 MRPL28 OPRM1 PBX4 PICK1 PLEKHA7 POF1B PPHLN1 PTEN RAB3IP SKIL TRAF2 TRIM27 TSC22D4 UBC UPRT USP7 VIM ZBTB26 ZNF165 ZNF213 ZNF263 ZNF474 ZSCAN1 ZSCAN16
Entrez ID		57684	5493
HPRD ID		15692	04187
Ensembl ID		ENSG00000171448	ENSG00000118898
Uniprot IDs		Q9HCK0	O60437
PDB IDs			4Q28
Enriched GO Terms of Interacting Partners?
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