USP29 and CLSPN

Data Source:
BioGRID (affinity chromatography technology, enzymatic study)

		USP29	CLSPN
Description		ubiquitin specific peptidase 29	claspin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus Cytosol	Nucleus Nucleoplasm Golgi Apparatus
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity	DNA Secondary Structure Binding Protein Binding Anaphase-promoting Complex Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein Phosphopantetheinylation	DNA Replication Checkpoint DNA Damage Checkpoint DNA Replication DNA Repair Mitotic G2 DNA Damage Checkpoint Protein Deubiquitination Peptidyl-serine Phosphorylation Activation Of Protein Kinase Activity Mitotic DNA Replication Checkpoint
Pathways			Apoptotic cleavage of cellular proteins Activation of ATR in response to replication stress Ub-specific processing proteases Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Urate levels in lean individuals ( 25811787)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		2 interacting genes: CLSPN HRAS	11 interacting genes: ATR BRCA1 CASP7 CDC7 CHEK1 FZR1 RAD9A USP20 USP28 USP29 USP7
Entrez ID		57663	63967
HPRD ID		07163	09257
Ensembl ID		ENSG00000131864	ENSG00000092853
Uniprot IDs		Q9HBJ7	Q9HAW4
PDB IDs
Enriched GO Terms of Interacting Partners?
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