MRTFB and KDM3A

Data Source:
BioGRID (pull down)

		MRTFB	KDM3A
Description		myocardin related transcription factor B	lysine demethylase 3A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Histone Deacetylase Complex Chromatin Nucleus Nucleoplasm Cytoplasm Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding Cadherin Binding	Transcription Coregulator Activity Iron Ion Binding Protein Binding Chromatin DNA Binding Histone Demethylase Activity (H3-K9 Specific) Androgen Receptor Binding Dioxygenase Activity
	Biological Process	Muscle Organ Development Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Transcription By RNA Polymerase II Smooth Muscle Cell Differentiation	Regulation Of Transcription By RNA Polymerase II Spermatid Nucleus Elongation Hormone-mediated Signaling Pathway Androgen Receptor Signaling Pathway Histone H3-K9 Demethylation Histone H3-K9 Dimethylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Formaldehyde Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Cold-induced Thermogenesis Cellular Response To Leukemia Inhibitory Factor Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Differentiation
Pathways			HDMs demethylate histones NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS			Atrial fibrillation ( 29892015) Glomerular filtration rate in chronic kidney disease ( 26420894) Ovarian cancer ( 30557369)
Interacting Genes		7 interacting genes: KDM3A MRTFA NCOA3 SMAD1 SMAD7 SRF SVIL	6 interacting genes: ETV2 H3C14 MRTFA MRTFB MYOCD RIPK2
Entrez ID		57496	55818
HPRD ID		17577	11054
Ensembl ID		ENSG00000186260	ENSG00000115548
Uniprot IDs		Q9ULH7	Q9Y4C1
PDB IDs
Enriched GO Terms of Interacting Partners?
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