PTBP1 and MIR143

Data Source:
BioGRID (unspecified method)

		PTBP1	MIR143
Description		polypyrimidine tract binding protein 1	microRNA 143
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Membrane Extracellular Exosome	Extracellular Space Extracellular Exosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Negative Regulation Of RNA Splicing Positive Regulation Of Protein Dephosphorylation Regulation Of RNA Splicing Regulation Of Cell Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation Positive Regulation Of Calcineurin-NFAT Signaling Cascade IRES-dependent Viral Translational Initiation	Regulation Of Smooth Muscle Contraction Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Activation Of Protein Kinase B Activity Gene Silencing By MiRNA Angiotensin-activated Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching Positive Regulation Of Angiogenesis Negative Regulation Of Glucose Import Negative Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Protein Kinase B Signaling Aorta Smooth Muscle Tissue Morphogenesis Regulation Of Phenotypic Switching Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Pulmonary Blood Vessel Remodeling
Pathways		FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Lymphocyte percentage of white cells ( 32888494) Red blood cell count ( 32888494) Refractive error ( 32231278) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		102 interacting genes: APBB1 APP CALCOCO2 CASP3 FUS H3-4 HIF1A HMGA1 HMGA2 HNRNPAB HNRNPL IL7R LINC00839 LINC01554 MARK4 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 SUMO2 ZMYM2	79 interacting genes: ADARB1 APOBEC3B C1QBP CDC5L CELF1 CPSF1 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SART3 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TUT4 U2SURP UPF1 UTP20 YBX1 YBX3 ZC3H10
Entrez ID		5725	406935
HPRD ID		02823
Ensembl ID		ENSG00000011304	ENSG00000284182
Uniprot IDs		P26599
PDB IDs		1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 2N3O 3ZZY 3ZZZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?