RAB25 and RAB11FIP3

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		RAB25	RAB11FIP3
Description		RAB25, member RAS oncogene family	RAB11 family interacting protein 3
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GO Annotations	Cellular Component	Endosome Pseudopodium Pseudopodium Membrane Cytoplasmic Vesicle Recycling Endosome Extracellular Exosome	Nucleoplasm Mitochondrion Endosome Centrosome Cytosol Endocytic Vesicle Midbody Cleavage Furrow Centriolar Satellite Intracellular Membrane-bounded Organelle Intercellular Bridge Recycling Endosome Recycling Endosome Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin V Binding	Calcium Ion Binding Protein Binding Small GTPase Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Epithelial Cell Morphogenesis Exocytosis Positive Regulation Of Cell Population Proliferation Positive Regulation Of Epithelial Cell Migration Protein Transport Pseudopodium Organization Regulation Of Vesicle-mediated Transport	Cell Cycle Vesicle-mediated Transport Endocytic Recycling Regulation Of Cytokinesis Cell Division Protein Localization To Cilium Negative Regulation Of Adiponectin Secretion
Pathways		RAB geranylgeranylation	VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Parkinson's disease ( 32201043)	Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494)
Interacting Genes		14 interacting genes: ACVR1 BMPR1B ITGB1 MED31 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SH3BP5L SMAD4 SMURF2 TGFBR1	9 interacting genes: ARF4 ARF5 ARF6 ASAP1 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34
Entrez ID		57111	9727
HPRD ID		06698	18521
Ensembl ID		ENSG00000132698	ENSG00000090565
Uniprot IDs		P57735	O75154
PDB IDs		2OIL 3TSO	2D7C 2HV8 4D0M 4UJ3 4UJ4
Enriched GO Terms of Interacting Partners?
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