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BAAT and PEX5
Data Source:
BioGRID
(unspecified method)
BAAT
PEX5
Description
bile acid-CoA:amino acid N-acyltransferase
peroxisomal biogenesis factor 5
Image
No pdb structure
GO Annotations
Cellular Component
Peroxisome
Peroxisomal Matrix
Cytosol
Cytoplasm
Peroxisome
Peroxisomal Membrane
Golgi Apparatus
Cytosol
Membrane
Protein-containing Complex
Molecular Function
Protein Binding
Palmitoyl-CoA Hydrolase Activity
N-acyltransferase Activity
Transferase Activity, Transferring Acyl Groups
Choloyl-CoA Hydrolase Activity
Acyl-CoA Hydrolase Activity
Glycine N-choloyltransferase Activity
Carboxylic Ester Hydrolase Activity
Medium-chain Acyl-CoA Hydrolase Activity
Long-chain Acyl-CoA Hydrolase Activity
Very Long Chain Acyl-CoA Hydrolase Activity
Myristoyl-CoA Hydrolase Activity
Peroxisome Targeting Sequence Binding
Peroxisome Matrix Targeting Signal-1 Binding
Protein Binding
Enzyme Binding
Small GTPase Binding
Peroxisome Membrane Targeting Sequence Binding
Protein N-terminus Binding
Protein Sequestering Activity
Biological Process
Liver Development
Bile Acid Conjugation
Glycine Metabolic Process
Protein Targeting To Peroxisome
Fatty Acid Metabolic Process
Acyl-CoA Metabolic Process
Bile Acid Biosynthetic Process
Bile Acid Metabolic Process
Taurine Metabolic Process
Animal Organ Regeneration
Protein Targeting To Peroxisome
Protein Import Into Peroxisome Matrix
Protein Import Into Peroxisome Matrix, Docking
Protein Ubiquitination
Negative Regulation Of Protein-containing Complex Assembly
Protein Import Into Peroxisome Membrane
Pathways
Recycling of bile acids and salts
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Peroxisomal protein import
Peroxisomal protein import
Pexophagy
Drugs
Glycine
Diseases
Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS
IgG glycosylation (
23382691
)
Night sleep phenotypes (
27126917
)
Refractive error (
32231278
)
Interacting Genes
24 interacting genes:
APC
AURKA
BCL10
BUB1
CDKN2A
CTNNA1
DLC1
ERBB2
GOLGA8DP
GOLGA8EP
GOLGA8F
MCC
MLH1
MLH3
MUTYH
ODC1
PDGFRL
PEX5
PTPRJ
RAD54B
RB1
SLC7A11
SMAD4
SRC
76 interacting genes:
ACD
ACOT2
ACOT4
ACOT8
ACOX2
ACOX3
AGXT
AMACR
ANKRD50
ATM
BAAT
BRCA1
CAPRIN2
CCDC14
CROT
DAO
DDO
DECR2
DHRS4
ECI2
EP400P1
EPHX2
GDPD5
GLMN
GNPAT
GSTK1
HACL1
HAO1
HAO2
HMGCL
HNRNPH1
HOXA7
HSPA1A
IDE
IDH1
LDHB
LONP2
MKRN3
MLYCD
MPV17
NOS2
NUDT19
NUDT3
NUDT7
PAOX
PDZK1
PEX1
PEX10
PEX12
PEX13
PEX14
PEX26
PEX6
PEX7
PIPOX
POT1
PRDX5
PRR13
PSAP
RPL14
S100A6
SCARB1
SCP2
SCRN2
SIRT3
SLC27A2
SNUPN
SSTR5
TIMMDC1
TINF2
TM6SF1
TOMM7
USP2
USP9X
ZFAND3
ZNF772
Entrez ID
570
5830
HPRD ID
08376
02684
Ensembl ID
ENSG00000136881
ENSG00000139197
Uniprot IDs
Q14032
A0A0S2Z480
A0A0S2Z4F3
A0A0S2Z4H1
B4DR50
B4E0T2
P50542
PDB IDs
1FCH
2C0L
2C0M
2J9Q
2W84
3R9A
4BXU
4KXK
4KYO
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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