COQ8A and DESI2

		COQ8A	DESI2
Description		coenzyme Q8A	desumoylating isopeptidase 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane Extrinsic Component Of Mitochondrial Inner Membrane	Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Kinase Activity ADP Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation	Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein Modification By Small Protein Removal Protein K48-linked Deubiquitination
Pathways
Drugs		Fostamatinib
Diseases		Coenzyme Q10 deficiency Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Interacting Genes		26 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM159 TMEM239 TPD52L2	11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7
Entrez ID		56997	51029
HPRD ID		07375	15153
Ensembl ID		ENSG00000163050	ENSG00000121644
Uniprot IDs		Q8NI60	A0A024R5P6 A0A024R5P9 Q9BSY9
PDB IDs		4PED 5I35
Enriched GO Terms of Interacting Partners?
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