C1GALT1 and GPR101

Data Source:
BioGRID (two hybrid)

		C1GALT1	GPR101
Description		core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	G protein-coupled receptor 101
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane	Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Protein Binding Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase Activity Metal Ion Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Angiogenesis Kidney Development O-glycan Processing O-glycan Processing, Core 1 Protein Phosphopantetheinylation Cell Differentiation	Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Pathways		Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Daytime sleep phenotypes ( 27126917) Diastolic blood pressure ( 30224653) Erosive tooth wear (severe vs non-severe) ( 29898447) FEV1 ( 30804560) Lung function (FEV1/FVC) ( 28166213 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Multiple sclerosis (severity) ( 19010793) Night sleep phenotypes ( 27126917) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Serum galactose-deficient IgA1 levels ( 28187132) Smooth-surface caries ( 24556642) Systolic blood pressure ( 26969751) Visceral adipose tissue adjusted for BMI ( 22589738)	Body mass index ( 28892062)
Interacting Genes		30 interacting genes: ANKS6 ARL13B C1GALT1C1 CD79A CPLX4 ELOVL4 FAM209A FAM210B GJA8 GJB1 GJB5 GPR101 GPR151 GPR42 GPRC5D GPX8 LEPROT LEUTX LHFPL5 MUC1 PIGP RETREG3 SLC14A1 SLC1A1 SLC7A14 STX1A TMEM14B TMEM237 TMEM52B XRN1	20 interacting genes: AGPAT4 C1GALT1 CDIPT CYB561A3 DERL3 LAT MFSD5 NDUFB11 ORMDL3 RTP2 SLC35E4 SLC39A9 SLC41A1 THSD7B TM4SF4 TMEM147 TMEM239 UNC93A UNC93B1 YIPF6
Entrez ID		56913	83550
HPRD ID		16631	02315
Ensembl ID		ENSG00000106392	ENSG00000165370
Uniprot IDs		A0A024RA32 Q9NS00	Q96P66
PDB IDs
Enriched GO Terms of Interacting Partners?
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