MAP3K7CL and USF1

Data Source:
BioGRID (two hybrid)

		MAP3K7CL	USF1
Description		MAP3K7 C-terminal like	upstream transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Enzyme Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process		Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Hypoxia Glucose Metabolic Process Regulation Of Transcription By RNA Polymerase II Response To UV Late Viral Transcription Cellular Response To Insulin Stimulus Glucose Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Carbon Catabolite Regulation Of Transcription Negative Regulation Of Fibrinolysis Lipid Homeostasis
Pathways			Estrogen-dependent gene expression
Drugs
Diseases			Familial combined hyperlipidemia (FCHL)
GWAS		Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Gamma glutamyl transferase levels ( 29403010) Ventricular ectopy ( 29618737) White blood cell count ( 32888494)	Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 23128233) Metabolite levels (lipoprotein measures) ( 27005778) Night sleep phenotypes ( 27126917)
Interacting Genes		9 interacting genes: AK8 CISH DDIT4L GPS2 KRT31 KRT34 REL TAB3 USF1	20 interacting genes: APP ESR1 FBXO7 FOS FOSL1 GTF2I HDAC9 HOMEZ LAP3 MAP3K7CL NFYA PLEKHF2 PPARGC1A PRKDC SNW1 TAOK2 TCF3 TCFL5 TRAF2 USF2
Entrez ID		56911	7391
HPRD ID		10764	01880
Ensembl ID		ENSG00000156265	ENSG00000158773
Uniprot IDs		B0EVZ6 B0EVZ7 B0EVZ8 B4DFW0 P57077	A0A0S2Z4U5 P22415
PDB IDs			1AN4
Enriched GO Terms of Interacting Partners?
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