SAR1A and NAT8

Data Source:
BioGRID (two hybrid)

		SAR1A	NAT8
Description		secretion associated Ras related GTPase 1A	N-acetyltransferase 8 (putative)
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding N-acetyltransferase Activity Cysteine-S-conjugate N-acetyltransferase Activity
	Biological Process	Regulation Of COPII Vesicle Coating Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Organization Membrane Organization Positive Regulation Of Protein Exit From Endoplasmic Reticulum COPII-coated Vesicle Cargo Loading	Glutathione Metabolic Process Positive Regulation Of Gene Expression Peptidyl-lysine N6-acetylation Response To Drug Negative Regulation Of Apoptotic Process Cellular Protein Metabolic Process Amyloid-beta Metabolic Process
Pathways			Amyloid fiber formation
Drugs
Diseases
GWAS			Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate ( 23535967) Glomerular filtration rate (creatinine) ( 28452372) Hemoglobin levels ( 32327693) Metabolic traits ( 21886157) Metabolite levels ( 21931564) Metabolite levels (X-11787) ( 23934736) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 24625756 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites ( 26352407)
Interacting Genes		69 interacting genes: ADGRE2 AIG1 ALG8 APP AQP1 AQP10 AQP3 ASGR1 ATXN1 BCL2L2 C14orf180 C3orf52 CD53 CD81 CES1 CLDN19 CLDND2 CLEC7A CMTM5 COL4A5 CTSA CXCL16 EMP3 ERG28 FAM3C GJB2 GOLT1B GRM2 GYPA HMOX2 JAGN1 LAT LHFPL5 MARCHF5 MIP MOSPD3 NAT8 NRM ORMDL1 PLLP PLN PLP2 RHOT2 RMDN2 SEC22A SERP1 SLC35A1 SMIM1 SNAP47 STX7 STX8 TMEM107 TMEM109 TMEM187 TMEM218 TMEM243 TMEM254 TMEM267 TMEM42 TMEM97 TRAF3 TRAM1L1 TTPA UBIAD1 UNC50 UPK1B VAMP3 VAMP4 VAMP5	29 interacting genes: ARL13B ATP6V0E1 BIK CD79A CERS4 CREB3L1 EBP FAM209A FFAR2 GOLT1A GPR152 HSD17B13 JPH1 LEPROTL1 LMNA MFSD14B MTIF3 REEP2 SAR1A SLC10A6 SMAD4 TGFBR1 TLCD4 TMEM143 TMEM14B TMEM31 TMX2 TSPAN31 YIPF4
Entrez ID		56681	9027
HPRD ID		07608	08413
Ensembl ID		ENSG00000079332	ENSG00000144035
Uniprot IDs		Q5SQT9 Q9NR31	Q9UHE5
PDB IDs		2GAO
Enriched GO Terms of Interacting Partners?
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