EIF5A2 and DHPS

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		EIF5A2	DHPS
Description		eukaryotic translation initiation factor 5A2	deoxyhypusine synthase
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Pore Endoplasmic Reticulum Membrane Cytosol Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol
	Molecular Function	Translation Elongation Factor Activity Protein Binding Ribosome Binding	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding
	Biological Process	Translational Elongation Spermatogenesis Positive Regulation Of Cell Population Proliferation Polyamine Homeostasis Protein Transport Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination MRNA Transport	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine
Pathways		Hypusine synthesis from eIF5A-lysine	Hypusine synthesis from eIF5A-lysine
Drugs			1-Guanidinium-7-Aminoheptane
Diseases
GWAS		C-reactive protein levels ( 30388399) Urate levels ( 31578528)	Platelet distribution width ( 32888494)
Interacting Genes		8 interacting genes: CDC23 DHPS HIF1A NIF3L1 PTBP2 RAB30 REL SDCBP	16 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 VASH1 ZNF138
Entrez ID		56648	1725
HPRD ID		10426	02969
Ensembl ID		ENSG00000163577	ENSG00000095059
Uniprot IDs		Q9GZV4	A0A024R7D0 A0A024R7E9 P49366
PDB IDs			1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM
Enriched GO Terms of Interacting Partners?
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