TMPRSS15 and GART

Data Source:
BioGRID (affinity chromatography technology)

		TMPRSS15	GART
Description		transmembrane serine protease 15	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
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GO Annotations	Cellular Component	Brush Border Membrane Integral Component Of Membrane	Cytosol Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding	Phosphoribosylamine-glycine Ligase Activity Phosphoribosylformylglycinamidine Cyclo-ligase Activity Phosphoribosylglycinamide Formyltransferase Activity ATP Binding Metal Ion Binding
	Biological Process	Proteolysis Endocytosis	Brainstem Development Purine Nucleotide Biosynthetic Process 'de Novo' IMP Biosynthetic Process Glycine Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Organic Substance Response To Inorganic Substance Cerebellum Development Cerebral Cortex Development Adenine Biosynthetic Process Tetrahydrofolate Biosynthetic Process
Pathways			Purine ribonucleoside monophosphate biosynthesis
Drugs			Pemetrexed Glycinamide Ribonucleotide N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid
Diseases		Enterokinase deficiency
GWAS		Asthma ( 29273806) Bulimia nervosa ( 23568457) Nucleus accumbens volume in trauma-exposed individuals ( 29187748)	Crohn's disease ( 23128233) Educational attainment ( 25201988) Psoriasis ( 25854761)
Interacting Genes		1 interacting genes: SPINK1	4 interacting genes: CDC42 KPNA2 PXN TRAF6
Entrez ID		5651	2618
HPRD ID		05972	00716
Ensembl ID		ENSG00000154646	ENSG00000159131
Uniprot IDs		P98073	P22102 Q59HH3
PDB IDs		4DGJ 6ZOV	1MEJ 1MEN 1MEO 1NJS 1RBM 1RBQ 1RBY 1RBZ 1RC0 1RC1 1ZLX 1ZLY 2QK4 2V9Y 4EW1 4EW2 4EW3 4ZYT 4ZYU 4ZYV 4ZYW 4ZYX 4ZYY 4ZYZ 4ZZ0 4ZZ1 4ZZ2 4ZZ3 5J9F
Enriched GO Terms of Interacting Partners?
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