TMPRSS15 and GABPA

Data Source:
BioGRID (affinity chromatography technology)

		TMPRSS15	GABPA
Description		transmembrane serine protease 15	GA binding protein transcription factor subunit alpha
Image			No pdb structure
GO Annotations	Cellular Component	Brush Border Membrane Integral Component Of Membrane	Chromatin Nucleus Nucleoplasm
	Molecular Function	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Activating Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Proteolysis Endocytosis	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Formation Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Gene Expression Cell Differentiation Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Dopamine
Pathways			Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases		Enterokinase deficiency
GWAS		Asthma ( 29273806) Bulimia nervosa ( 23568457) Nucleus accumbens volume in trauma-exposed individuals ( 29187748)	Gout (normal type) ( 32238385) Nicotine dependence symptom count ( 25555482)
Interacting Genes		1 interacting genes: SPINK1	13 interacting genes: APP ATF1 CREBBP EP300 GABPB1 GABPB2 HCFC1 MED1 PINX1 SP1 SP3 STK16 ZC2HC1B
Entrez ID		5651	2551
HPRD ID		05972	11793
Ensembl ID		ENSG00000154646	ENSG00000154727
Uniprot IDs		P98073	A8IE48 Q06546 Q8IYS3
PDB IDs		4DGJ 6ZOV
Enriched GO Terms of Interacting Partners?
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