NSFL1C and SRP14

Data Source:
HPRD (two hybrid)

		NSFL1C	SRP14
Description		NSFL1 cofactor	signal recognition particle 14
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Golgi Stack Cytosol Plasma Membrane Spindle Pole Centrosome Intermediate Filament Cytoskeleton VCP-NSFL1C Complex	Extracellular Region Nucleus Cytoplasm Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Phospholipid Binding Ubiquitin Binding ATPase Binding	RNA Binding Protein Binding 7S RNA Binding Endoplasmic Reticulum Signal Peptide Binding
	Biological Process	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Neutrophil Degranulation Protein Targeting To ER
Pathways			SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Neutrophil degranulation
Drugs			Artenimol
Diseases
GWAS			Ewing sarcoma ( 22327514) Obesity-related traits ( 23251661) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		16 interacting genes: ANP32A CDK1 DBI FAM32A GLMN GSK3B LIPE NGLY1 PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP	7 interacting genes: CALM1 EAF1 IL7R NSFL1C PTEN SPANXN2 SRP9
Entrez ID		55968	6727
HPRD ID		09425	02831
Ensembl ID		ENSG00000088833	ENSG00000140319
Uniprot IDs		Q53FE8 Q9UNZ2	P37108
PDB IDs		1SS6	1E8O 1E8S 1RY1 4UYJ 4UYK 5AOX
Enriched GO Terms of Interacting Partners?
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