DCAF6 and GTF2IRD1

Data Source:
BioGRID (two hybrid)

		DCAF6	GTF2IRD1
Description		DDB1 and CUL4 associated factor 6	GTF2I repeat domain containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Nuclear Receptor Coactivator Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Protein Ubiquitination Post-translational Protein Modification Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Transition Between Slow And Fast Fiber
Pathways		Neddylation
Drugs
Diseases
GWAS		Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Schizophrenia ( 22037555)	Age at suicide ( 31476763) Aluminium levels ( 26025379) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Severe influenza A (H1N1) infection ( 26379185) SjÃ¶gren's syndrome ( 24097066) Systemic lupus erythematosus ( 26663301 28714469) Triglyceride levels ( 32203549)
Interacting Genes		13 interacting genes: ACVR1 AR BMPR1B CLIP4 CUL4A GTF2IRD1 MDFI NR3C1 SMAD2 SUPT5H TGFBR1 TRIM55 TRIM63	24 interacting genes: ALMS1 ATP2C1 CDK20 DCAF6 EXOSC4 GORASP2 HDAC3 HTRA4 KPNA1 KPNA2 KPNA3 KPNA4 MRFAP1L1 PIAS1 PIAS2 PIP4P2 PKP1 PKP2 SELENOS SMAD3 SPTLC1 UBC USP20 ZMYM5
Entrez ID		55827	9569
HPRD ID		17156	08379
Ensembl ID		ENSG00000143164	ENSG00000006704
Uniprot IDs		Q58WW2	E9PFE2 Q9UHL9
PDB IDs		3I7O	2D99 2DN5 2DZQ 2DZR
Enriched GO Terms of Interacting Partners?
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