DEPDC1B and RGS3

Data Source:
BioGRID (two hybrid)

		DEPDC1B	RGS3
Description		DEP domain containing 1B	regulator of G protein signaling 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytosol Plasma Membrane
	Molecular Function	GTPase Activator Activity	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Cell Migration Positive Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Inactivation Of MAPK Activity Signal Transduction G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		Rho GTPase cycle	G alpha (q) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)	Height ( 28552196) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: CDC23 EBPL GRIP1 PTPRF RGS3 UHMK1	24 interacting genes: ACD APP CNKSR2 CYSRT1 DEPDC1B EFNB1 EFNB2 ESR1 GLS2 GNA11 GNAI3 GORASP2 GRIN2A HES4 HIPK3 MAPK12 PAX6 PLSCR1 PRKN SCN5A YWHAB YWHAE YWHAQ YWHAZ
Entrez ID		55789	5998
HPRD ID		16794	03720
Ensembl ID		ENSG00000035499	ENSG00000138835
Uniprot IDs		Q8WUY9	A0A024R831 A0A024R833 A0A024R841 B3KVT7 B3KWG8 H7BXY1 P49796 Q53GP3
PDB IDs			2F5Y 2OJ4 3FBK
Enriched GO Terms of Interacting Partners?
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