CEP72 and SPATA24

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		CEP72	SPATA24
Description		centrosomal protein 72	spermatogenesis associated 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Centriolar Satellite	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	DNA Binding Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Spindle Organization Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Gamma-tubulin Complex Localization Ciliary Basal Body-plasma Membrane Docking Regulation Of Protein Localization To Centrosome	Multicellular Organism Development Spermatogenesis Cell Differentiation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Esophageal adenocarcinoma ( 27527254) Lung disease severity in cystic fibrosis ( 26417704) Obesity-related traits ( 23251661) Ulcerative colitis ( 28067908 20228799) Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia ( 25710658)	Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Malaria ( 31844061)
Interacting Genes		23 interacting genes: ATXN7 CATIP CHCHD3 FAM161A FAM90A1 GOLGA6L9 IGHM IL16 INCA1 KIAA0408 LNX1 MCM10 NME7 PCM1 PIN4 PSMA1 SPATA2 SPATA24 SRSF2 STAMBPL1 ZBTB16 ZNF417 ZNF688	24 interacting genes: CALCOCO2 CAMK2D CEP72 CTNNBIP1 CYSRT1 EFEMP2 EHD2 FLOT2 KDM1A KRT31 KRT40 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP4-2 LZTS2 MDFI MID2 NBPF19 NOTCH2NLA OIP5 PLEKHF2 PTAFR SUV39H1
Entrez ID		55722	202051
HPRD ID		07685	19510
Ensembl ID		ENSG00000112877	ENSG00000170469
Uniprot IDs		Q9P209	Q86W54
PDB IDs
Enriched GO Terms of Interacting Partners?
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