TSR1 and CIDEB

Data Source:
BioGRID (two hybrid)

		TSR1	CIDEB
Description		TSR1 ribosome maturation factor	cell death inducing DFFA like effector b
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Preribosome, Small Subunit Precursor	Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding U3 SnoRNA Binding	Protein Binding Identical Protein Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Viral Process Response To Nutrient Levels Bile Acid Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Aortic root size ( 19584346) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 25056061 29483656)	Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		4 interacting genes: BMPR2 CIDEB RHBDD2 SUMO2	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 C5orf38 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		55720	27141
HPRD ID		07681	11981
Ensembl ID		ENSG00000167721	ENSG00000136305
Uniprot IDs		Q2NL82	Q9UHD4
PDB IDs		6G18 6G4S 6G4W 6G51 6G53 6ZMT 6ZN5	1D4B
Enriched GO Terms of Interacting Partners?
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