POLR3E and POLR3A

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		POLR3E	POLR3A
Description		RNA polymerase III subunit E	RNA polymerase III subunit A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol	Nucleoplasm RNA Polymerase III Complex Cytosol Membrane
	Molecular Function	DNA-directed 5'-3' RNA Polymerase Activity	DNA Binding Chromatin Binding DNA-directed 5'-3' RNA Polymerase Activity Metal Ion Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Type I Interferon Production Innate Immune Response Defense Response To Virus	Transcription, DNA-templated Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Defense Response To Virus
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Height ( 31562340) L-selectin levels ( 25576479)	Colorectal cancer or advanced adenoma ( 30510241) Executive function (trail making test B) ( 24629169)
Interacting Genes		2 interacting genes: POLR3A POLR3D	6 interacting genes: EWSR1 IKBKG NEDD4 PCBD1 PKP2 POLR3E
Entrez ID		55718	11128
HPRD ID		15155	17879
Ensembl ID		ENSG00000058600	ENSG00000148606
Uniprot IDs		A0A0C4DH01 Q9NVU0	O14802
PDB IDs
Enriched GO Terms of Interacting Partners?
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