LUC7L and FBXO25

Data Source:
BioGRID (enzymatic study)

		LUC7L	FBXO25
Description		LUC7 like	F-box protein 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	U1 SnRNP U2-type Prespliceosome	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	MRNA Binding Protein Binding Identical Protein Binding	Actin Binding Ubiquitin-protein Transferase Activity
	Biological Process	MRNA Splice Site Selection	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Hemoglobin concentration ( 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 28453575 20139978 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		12 interacting genes: ANTKMT APPL1 CALM1 CHERP CTNNBL1 FBXO25 GADD45G PRDX1 PRMT5 SRSF6 SRSF7 TCERG1	82 interacting genes: ANKRD13A APLF AXL BMX BRME1 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GRK2 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ILRUN ING3 IRS1 JHY KDR KRT8 LMCD1 LUC7L MAT2B NKX2-5 NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TBX5 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		55692	26260
HPRD ID		08476	16439
Ensembl ID		ENSG00000007392	ENSG00000147364
Uniprot IDs		A8MYV2 D3DU41 Q1W6G4 Q9NQ29	A0A024QZ88 Q8TCJ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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