PEX26 and PEX14

Data Source:
BioGRID (fluorescent resonance energy transfer)

		PEX26	PEX14
Description		peroxisomal biogenesis factor 26	peroxisomal biogenesis factor 14
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane	Fibrillar Center Nucleus Peroxisome Peroxisomal Membrane Membrane Integral Component Of Membrane Protein-containing Complex Peroxisomal Importomer Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Protein-containing Complex Binding ATPase Binding	Transcription Corepressor Activity Signaling Receptor Binding Protein Binding Microtubule Binding Identical Protein Binding Protein N-terminus Binding Beta-tubulin Binding
	Biological Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Membrane	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Ubiquitination Negative Regulation Of Protein Binding Microtubule Anchoring Peroxisome Transport Along Microtubule Negative Regulation Of DNA-binding Transcription Factor Activity Protein Import Into Peroxisome Matrix, Substrate Release Negative Regulation Of Transcription, DNA-templated Protein-containing Complex Assembly
Pathways		Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import	E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS			Asthma ( 27182965 32296059) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 29059683 23535729 23535733 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Breast size ( 27182965) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Facial morphology ( 31763980) Hand grip strength ( 29313844) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Optic nerve measurement (rim area) ( 20395239) Prostate cancer ( 25217961) Refractive error ( 32231278) Self-reported allergy ( 23817569) Total cholesterol levels ( 30275531)
Interacting Genes		6 interacting genes: PEX1 PEX14 PEX19 PEX5 PEX6 SUFU	14 interacting genes: CENPK COPS4 GET3 HDAC1 MARF1 MED8 MTNR1A NFE2 PEX19 PEX26 PEX5 PEX7 SMARCC2 ZHX1
Entrez ID		55670	5195
HPRD ID		10559	03477
Ensembl ID		ENSG00000215193	ENSG00000142655
Uniprot IDs		A0A024R100 A0A0S2Z5M7 Q7Z2D7 Q7Z412	O75381
PDB IDs			2W84 2W85 4BXU
Enriched GO Terms of Interacting Partners?
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