PRR5 and SCUBE1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		PRR5	SCUBE1
Description		proline rich 5	signal peptide, CUB domain and EGF like domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol TORC2 Complex	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Extrinsic Component Of Plasma Membrane
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Identical Protein Binding
	Biological Process	Cell Cycle Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Activation Of Protein Kinase B Activity TORC2 Signaling	Inflammatory Response Signal Transduction Adult Heart Development Blood Coagulation Post-embryonic Development Extracellular Matrix Disassembly Endothelial Cell Differentiation Positive Regulation Of Smoothened Signaling Pathway
Pathways		PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation	Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)	Blood protein levels ( 30072576) Molar-incisor hypomineralization ( 23918034) Response to fenofibrate (adiponectin levels) ( 23149075) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		5 interacting genes: CTNNA3 DESI1 GPSM3 HGS USHBP1	2 interacting genes: SCUBE2 SCUBE3
Entrez ID		55615	80274
HPRD ID		18696	18029
Ensembl ID		ENSG00000186654	ENSG00000159307
Uniprot IDs		A0A024R4U5 A8K699 P85299	A0JP65 Q6ZS56 Q86TI6 Q8IWY4
PDB IDs
Enriched GO Terms of Interacting Partners?
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