PRR5 and GPSM3

Data Source:
BioGRID (two hybrid)

		PRR5	GPSM3
Description		proline rich 5	G protein signaling modulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol TORC2 Complex	Cellular_component Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding	Molecular_function Protein Binding GTPase Regulator Activity
	Biological Process	Cell Cycle Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Activation Of Protein Kinase B Activity TORC2 Signaling	Positive Regulation Of Leukocyte Chemotaxis Biological_process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation	G alpha (i) signalling events
Drugs
Diseases
GWAS		Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)	Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908)
Interacting Genes		5 interacting genes: CTNNA3 DESI1 GPSM3 HGS USHBP1	45 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C10orf82 C11orf45 C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 YWHAZ ZNF20 ZNF581
Entrez ID		55615	63940
HPRD ID		18696	13605
Ensembl ID		ENSG00000186654	ENSG00000213654
Uniprot IDs		A0A024R4U5 A8K699 P85299	A0A024RCP6 Q9Y4H4
PDB IDs
Enriched GO Terms of Interacting Partners?
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