PRR5 and WNT7B

Data Source:
BioGRID (biochemical)

		PRR5	WNT7B
Description		proline rich 5	Wnt family member 7B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol TORC2 Complex	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Lumen Plasma Membrane Endocytic Vesicle Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Frizzled Binding Cytokine Activity Protein Binding Receptor Ligand Activity
	Biological Process	Cell Cycle Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Activation Of Protein Kinase B Activity TORC2 Signaling	In Utero Embryonic Development Metanephros Morphogenesis Wnt Signaling Pathway Establishment Or Maintenance Of Polarity Of Embryonic Epithelium Forebrain Regionalization Central Nervous System Vasculogenesis Neuron Differentiation Lung Development Oxygen Homeostasis Homeostatic Process Cellular Metabolic Process Cell Fate Commitment Positive Regulation Of Osteoblast Differentiation Positive Regulation Of JNK Cascade Fibroblast Proliferation Embryonic Organ Development Synapse Organization Canonical Wnt Signaling Pathway Lung Morphogenesis Lung Epithelium Development Lobar Bronchus Development Trachea Cartilage Morphogenesis Developmental Growth Involved In Morphogenesis Embryonic Placenta Morphogenesis Chorio-allantoic Fusion Mammary Gland Epithelium Development Lens Fiber Cell Development Cellular Response To Retinoic Acid Renal Inner Medulla Development Renal Outer Medulla Development Outer Medullary Collecting Duct Development Inner Medullary Collecting Duct Development Stem Cell Proliferation Metanephric Collecting Duct Development Metanephric Epithelium Development Metanephric Loop Of Henle Development
Pathways		PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation	WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)	Body mass index ( 25760438) Central corneal thickness ( 28171582 29847655) Corneal curvature ( 25823570) Dupuytren's disease ( 28886342 21732829) Heel bone mineral density ( 30598549) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Macular thickness ( 30535121) Optic disc size ( 31809533) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278) Rosacea symptom severity ( 29771307) Type 2 diabetes ( 32499647)
Interacting Genes		5 interacting genes: CTNNA3 DESI1 GPSM3 HGS USHBP1	5 interacting genes: CASK CUL3 ELOC GPC3 PORCN
Entrez ID		55615	7477
HPRD ID		18696	03573
Ensembl ID		ENSG00000186654	ENSG00000188064
Uniprot IDs		A0A024R4U5 A8K699 P85299	A8K0G1 P56706
PDB IDs
Enriched GO Terms of Interacting Partners?
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