PPP3CC and AMPH

Data Source:
BioGRID (two hybrid)

		PPP3CC	AMPH
Description		protein phosphatase 3 catalytic subunit gamma	amphiphysin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Calcineurin Complex Presynapse Glutamatergic Synapse	Cytosol Plasma Membrane Synaptic Vesicle Actin Cytoskeleton Synaptic Vesicle Membrane Leading Edge Membrane
	Molecular Function	Protein Binding Calmodulin Binding Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding Phospholipid Binding
	Biological Process	Protein Dephosphorylation Brain Development Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Positive Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Endocytosis Chemical Synaptic Transmission Synaptic Vesicle Endocytosis Membrane Organization
Pathways		Activation of BAD and translocation to mitochondria DARPP-32 events	Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) HIV-1 viral setpoint ( 20205591) Verbal declarative memory ( 25648963)	Ankylosing spondylitis ( 30946743) Bitter non-alcoholic beverage consumption ( 31046077) Cerebral microbleeds ( 31209788) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		14 interacting genes: AMPH APP BCL2 BMPR1B CABIN1 CSNK2B HAX1 ITPKC PPP3R1 SDC2 SPATA33 TGFBR1 THAP7 UNC119	27 interacting genes: AP2A2 ARL16 BIN1 CABIN1 CDK1 CDK5 CDK5R1 CLTC DEUP1 DNM1 DNM2 DYRK1A ITSN2 KHDRBS1 MAPK6 MAPT NECAP1 PLD2 PPP3CA PPP3CC SH3GL2 SH3GLB1 SYN1 SYNJ1 TERF1 UBC VTN
Entrez ID		5533	273
HPRD ID		00236	02687
Ensembl ID		ENSG00000120910	ENSG00000078053
Uniprot IDs		P48454	P49418
PDB IDs			1KY7 1UTC 3SOG 4ATM 5M5S 5M61
Enriched GO Terms of Interacting Partners?
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