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PEF1 and PDCD6
Data Source:
HPRD
(in vivo)
PEF1
PDCD6
Description
penta-EF-hand domain containing 1
programmed cell death 6
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Cytoplasm
Endoplasmic Reticulum
COPII Vesicle Coat
Cul3-RING Ubiquitin Ligase Complex
Extracellular Exosome
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
COPII Vesicle Coat
Cytoplasmic Vesicle
Cul3-RING Ubiquitin Ligase Complex
Extracellular Exosome
Endoplasmic Reticulum Exit Site
Molecular Function
RNA Binding
Calcium Ion Binding
Protein Binding
Identical Protein Binding
Protein Heterodimerization Activity
Protein Dimerization Activity
Calcium-dependent Protein Binding
Ubiquitin Ligase-substrate Adaptor Activity
Magnesium Ion Binding
Calcium Ion Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Protein Homodimerization Activity
Protein-membrane Adaptor Activity
Protein Dimerization Activity
Calcium-dependent Protein Binding
Ubiquitin Ligase-substrate Adaptor Activity
Biological Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Neural Crest Formation
Neural Crest Cell Development
Protein Ubiquitination
COPII Vesicle Coating
Response To Calcium Ion
Positive Regulation Of Protein Monoubiquitination
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Endothelial Cell Migration
Neural Crest Formation
Neural Crest Cell Development
Protein Ubiquitination
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of TOR Signaling
Cellular Response To Heat
Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
COPII Vesicle Coating
Response To Calcium Ion
Negative Regulation Of Protein Kinase B Signaling
Apoptotic Signaling Pathway
Positive Regulation Of Protein Monoubiquitination
Pathways
Drugs
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Calcium
Zinc
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Zinc acetate
Diseases
GWAS
Asthma (
31959851
)
Body mass index (
26426971
)
Cognitive ability (
29186694
)
Cognitive ability (MTAG) (
29186694
)
General cognitive ability (
29844566
)
Intelligence (MTAG) (
29326435
)
Severe aortic features in Marfan syndrome (
30087447
)
Interacting Genes
40 interacting genes:
AKAP8L
ALG2
ANKRD10
BAG4
BPIFA1
C11orf1
CALCOCO2
CEP55
CTAG1A
CTAG1B
CUL3
DAZAP2
DMRTB1
EIF4G1
EWSR1
FAM168A
FOXR2
HEMK1
HGS
HYDIN
INCA1
KLHL12
KRTAP12-1
KRTAP15-1
KRTAP19-1
MED25
METTL15
NR0B2
PDCD6
SEC24A
SEC31A
SMUG1
SOHLH1
SPAG8
SPG21
STH
TFG
VPS37C
WWOX
ZIC1
22 interacting genes:
ANXA11
ANXA7
BAG4
CDKN2A
CPNE1
CPNE2
CPNE4
CUL3
FAS
FASLG
HEBP2
IGFALS
MAP3K5
MAPK1IP1L
PDCD6IP
PEF1
PRR19
SEC31A
SH3KBP1
TIMM22
VPS37C
YWHAQ
Entrez ID
553115
10016
HPRD ID
10143
03035
Ensembl ID
ENSG00000162517
ENSG00000249915
Uniprot IDs
A0A384MQX5
Q9UBV8
A0A024QZ42
A0A087WZ38
O75340
Q53FC3
PDB IDs
2ZN8
2ZN9
2ZND
2ZNE
2ZRS
2ZRT
3AAJ
3AAK
3WXA
5GQQ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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